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Dnaic2
Gene Detail
Symbol

Name
ID
Dnaic2
dynein, axonemal, intermediate chain 2
MGI:2685574
Synonyms
C030015H18Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 11
80.19 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:114727408-114757889 bp, + strand
From VEGA annotation of GRCm38

  30482 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11311  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: DNAI2
Gene Tree: Dnaic2

Human
homologs
DNAI2, dynein, axonemal, intermediate chain 2
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 64446
neXtProt AC: NX_Q9GZS0

Human Synonyms: CILD9, DIC2

Human Chr (Location): 17q25; chr17:74274232-74314884 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human DNAI2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Gene trapped(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Dnaic2 interacts with 83 markers (Mir18, Mir18b, Mir29a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process cell projection organization, cilium assembly, ...
Component axonemal dynein complex, axoneme, ...
Function microtubule motor activity, motor activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
cDNA source data(11)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase dnai2    NEW 
Molecular
reagents
All nucleic(13) cDNA(11) Other(2)
Microarray probesets(1)
Other database
links
VEGA Gene Model OTTMUSG00000003426 (Evidence)
Ensembl Gene Model ENSMUSG00000034706 (Evidence)
Entrez Gene 432611 (Evidence)
UniGene 212764
DFCI TC1592219, TC1681755, TC1616770, TC1659205, TC1774359
DoTS DT.97382785, DT.91420661, DT.91334575, DT.55196261, DT.40167566
NIA Mouse Gene Index U013525
Consensus CDS Project CCDS36366.1
International Mouse Phenotyping Consortium Status Dnaic2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003426 VEGA Gene Model | MGI Sequence Detail 30482 C57BL/6J ±  kb
transcript OTTMUST00000007219 VEGA | MGI Sequence Detail 2874 Not Applicable 
polypeptide OTTMUSP00000003476 VEGA | MGI Sequence Detail 623 Not Applicable 

For the selected sequences
All sequences(56) RefSeq(11) UniProt(3)
Polymorphisms
SNPs within 2kb(87 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001680 WD40 repeat
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000006569 dynein intermediate chain 2, axonemal
References
(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:208266 Dong F, et al., Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm. J Cell Biol. 2014 Jan 20;204(2):203-13
All references(25)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory