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Pcdh19
Gene Detail
Symbol

Name
ID
Pcdh19
protocadherin 19
MGI:2685563
Synonyms
B530002L05Rik, LOC279653, mKIAA1313
Feature Type
protein coding gene
Genetic Map
Chromosome X
55.21 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
ChrX:133582860-133688987 bp, - strand
From VEGA annotation of GRCm38

  106128 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:18916  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: PCDH19
Gene Tree: Pcdh19

Human
homologs
PCDH19, protocadherin 19
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 57526
neXtProt AC: NX_Q8TAB3

Human Synonyms: EFMR, EIEE9

Human Chr (Location): Xq22.1; chrX:100291644-100410273 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human PCDH19

Interactions
Pcdh19 interacts with 521 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process brain development, cell adhesion, ...
Component integral component of membrane, membrane, ...
Function calcium ion binding
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (98)    Tissues (82)    Images (27)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 98
cDNA source data(33)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA PCDH19 ; Xenbase pcdh19 ; ZFIN pcdh19    NEW 
Molecular
reagents
All nucleic(34) cDNA(33) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000018675 (Evidence)
Ensembl Gene Model ENSMUSG00000051323 (Evidence)
Entrez Gene 279653 (Evidence)
UniGene 39738
DFCI TC1598312, TC1644381
DoTS DT.40143719, DT.97371400
NIA Mouse Gene Index U039691
Consensus CDS Project CCDS41117.1, CCDS53181.1
International Mouse Phenotyping Consortium Status Pcdh19
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018675 VEGA Gene Model | MGI Sequence Detail 106128 C57BL/6J ±  kb
transcript OTTMUST00000044950 VEGA | MGI Sequence Detail 10289 Not Applicable 
polypeptide OTTMUSP00000020199 VEGA | MGI Sequence Detail 1145 Not Applicable 

For the selected sequences
All sequences(51) RefSeq(12) UniProt(4)
Polymorphisms
SNPs within 2kb(324 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002126 Cadherin
InterPro IPR020894 Cadherin conserved site
InterPro IPR015919 Cadherin-like
InterPro IPR013164 Cadherin, N-terminal
Protein Ontology PR:000012349 protocadherin-19
References
(Earliest) J:83413 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Feb 28;10(1):35-48
(Latest) J:202352 Boualia SK, et al., A core transcriptional network composed of Pax2/8, Gata3 and Lim1 regulates key players of pro/mesonephros morphogenesis. Dev Biol. 2013 Oct 15;382(2):555-66
All references(29)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory