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Stkld1 Gene Detail
Summary
  • Symbol
    Stkld1
  • Name
    serine/threonine kinase-like domain containing 1
  • Synonyms
    Gm711, LOC279029
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685557
    NCBI Gene: 279029
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:26934047-26953496 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 19.12 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    60 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685557
protein coding gene Chr2:26933519-26953496 (.)
129S1/SvImJ MGP_129S1SvImJ_G0025503
protein coding gene Chr2:24905762-24926631 (+)
A/J MGP_AJ_G0025480
protein coding gene Chr2:23961578-23981521 (+)
AKR/J MGP_AKRJ_G0025450
protein coding gene Chr2:24742129-24762107 (+)
BALB/cJ MGP_BALBcJ_G0025476
protein coding gene Chr2:24079911-24099294 (+)
C3H/HeJ MGP_C3HHeJ_G0025237
protein coding gene Chr2:24680875-24705265 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025920
protein coding gene Chr2:25747522-25768737 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023331
protein coding gene Chr2:22800560-22820485 (+)
CAST/EiJ MGP_CASTEiJ_G0024700
protein coding gene Chr2:24561020-24583680 (+)
CBA/J MGP_CBAJ_G0025215
protein coding gene Chr2:26641950-26666323 (+)
DBA/2J MGP_DBA2J_G0025348
protein coding gene Chr2:23778840-23802969 (+)
FVB/NJ MGP_FVBNJ_G0025310
protein coding gene Chr2:23536995-23556904 (+)
LP/J MGP_LPJ_G0025434
protein coding gene Chr2:24851124-24871662 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025341
protein coding gene Chr2:26700181-26719786 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025979
protein coding gene Chr2:24684374-24704143 (+)
PWK/PhJ MGP_PWKPhJ_G0024448
protein coding gene Chr2:23572211-23592092 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024248
protein coding gene Chr2:24835871-24855249 (+)
WSB/EiJ MGP_WSBEiJ_G0024769
protein coding gene Chr2:24804778-24825565 (+)



Homology
more
  • Human Ortholog
    STKLD1, serine/threonine kinase like domain containing 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    STKLD1, serine/threonine kinase like domain containing 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C9orf96, SgK071, Sk521
  • Links
    NCBI Gene ID: 169436
    neXtProt AC: NX_Q8NE28
    UniProt: Q8NE28

  • Chr Location
    9q34.2; chr9:133376413-133406096 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000049897 Ensembl Gene Model | MGI Sequence Detail 19450 C57BL/6J ±  kb
transcript ENSMUST00000055406 Ensembl | MGI Sequence Detail 2169 Not Applicable  
polypeptide ENSMUSP00000062967 Ensembl | MGI Sequence Detail 662 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000014789 serine/threonine kinase-like domain-containing protein STKLD1
  • InterPro Domains
    IPR016024 Armadillo-type fold
    IPR000719 Protein kinase domain
    IPR011009 Protein kinase-like domain superfamily
    IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domain
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
References
more
  • Summaries
    All 25
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory