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Stkld1 Gene Detail
Summary
  • Symbol
    Stkld1
  • Name
    serine/threonine kinase-like domain containing 1
  • Synonyms
    Gm711, LOC279029
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685557
    NCBI Gene: 279029
Location & Maps
more
  • Sequence Map
    Chr2:26934047-26953496 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      19450 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 19.12 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    STKLD1, serine/threonine kinase like domain containing 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    STKLD1, serine/threonine kinase like domain containing 1
    Orthology source: HomoloGene
  • Synonyms
    C9orf96, SgK071, Sk521
  • Links
    NCBI Gene ID: 169436
    neXtProt AC: NX_Q8NE28

  • Chr Location
    9q34.2; chr9:133376413-133406096 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000011848 VEGA Gene Model | MGI Sequence Detail 19450 C57BL/6J ±  kb
transcript OTTMUST00000027845 VEGA | MGI Sequence Detail 2169 Not Applicable  
polypeptide OTTMUSP00000012647 VEGA | MGI Sequence Detail 662 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    60 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000014789 serine/threonine kinase-like domain-containing protein STKLD1
  • InterPro Domains
    IPR011989 Armadillo-like helical
    IPR016024 Armadillo-type fold
    IPR000719 Protein kinase domain
    IPR011009 Protein kinase-like domain
    IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory