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Wfdc8 Gene Detail
Summary
  • Symbol
    Wfdc8
  • Name
    WAP four-disulfide core domain 8
  • Synonyms
    LOC277343
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685552
    NCBI Gene: 277343
Location & Maps
more
  • Sequence Map
    Chr2:164596458-164613626 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      17169 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 85.22 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    WFDC8, WAP four-disulfide core domain 8
  • Vertebrate Orthologs
    7
  • Human Ortholog
    WFDC8, WAP four-disulfide core domain 8
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C20orf170, dJ461P17.1, HEL-S-292, WAP8
  • Links
    NCBI Gene ID: 90199
    neXtProt AC: NX_Q8IUA0

  • Chr Location
    20q13.12; chr20:45551152-45579350 (-)  GRCh38.p2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    13
  • Tissues
    13
  • cDNA Data
    1
  • Literature Summary
    1
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001096 VEGA Gene Model | MGI Sequence Detail 17169 C57BL/6J ±  kb
transcript OTTMUST00000039136 VEGA | MGI Sequence Detail 3227 Not Applicable  
polypeptide OTTMUSP00000017483 VEGA | MGI Sequence Detail 426 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    220 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000031266 WAP four-disulfide core domain protein 8
  • InterPro Domains
    IPR002223 Pancreatic trypsin inhibitor Kunitz domain
    IPR020901 Proteinase inhibitor I2, Kunitz, conserved site
    IPR008197 WAP-type 'four-disulfide core' domain
Molecular
Reagents
less
  • All nucleic 4
    cDNA 1
    Primer pair 1
    Other 2

    Microarray probesets 1
References
more
  • Summaries
    All 18
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 1
  • Earliest
    J:84763 Sivashanmugam P, et al., Characterization of mouse Eppin and a gene cluster of similar protease inhibitors on mouse chromosome 2. Gene. 2003 Jul 17;312:125-34
  • Latest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/20/2016
MGI 6.05 		The Jackson Laboratory