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Fam131c Gene Detail
Summary
  • Symbol
    Fam131c
  • Name
    family with sequence similarity 131, member C
  • Synonyms
    LOC277743
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685539
    NCBI Gene: 277743
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:141095531-141111486 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 73.88 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    629 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685539
 protein coding gene Chr4:141095503-141111486 (+)
129S1/SvImJ ENSMUSG00200042837
 protein coding gene Chr4:134520706-134535993 (+)
A/J ENSMUSG00195033294
 protein coding gene Chr4:135861473-135877431 (+)
AKR/J ENSMUSG00220046337
 protein coding gene Chr4:134862261-134878219 (+)
BALB/cJ ENSMUSG00180040318
 protein coding gene Chr4:133502549-133518505 (+)
C3H/HeJ ENSMUSG00175037047
 protein coding gene Chr4:134529121-134545076 (+)
C57BL/6NJ ENSMUSG00215047526
 protein coding gene Chr4:136047020-136062975 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026739
 protein coding gene Chr4:131048807-131065189 (+)
CAST/EiJ ENSTCUG00005012803
 protein coding gene Chr4:135486569-135502578 (+)
CBA/J ENSMUSG00210026503
 protein coding gene Chr4:134153031-134168985 (+)
DBA/2J ENSMUSG00185049724
 protein coding gene Chr4:135666025-135681316 (+)
FVB/NJ ENSMUSG00205018160
 protein coding gene Chr4:133917215-133932503 (+)
JF1/MsJ ENSUMUG00000042881
 protein coding gene Chr4:136350225-136366169 (+)
LP/J ENSMUSG00230038140
 protein coding gene Chr4:139459089-139474731 (+)
NOD/ShiLtJ ENSMUSG00190027245
 protein coding gene Chr4:133912761-133928048 (+)
NZO/HlLtJ ENSMUSG00225009975
 protein coding gene Chr4:145404239-145419857 (+)
PWK/PhJ ENSLUMG00010045415
 protein coding gene Chr4:133351467-133366757 (+)
SPRET/EiJ ENSMSPG00010025028
 protein coding gene Chr4:135393495-135409792 (+)
WSB/EiJ ENSIUOG00005045381
 protein coding gene Chr4:133799021-133814313 (+)



Homology
more
  • Human Ortholog
    FAM131C, family with sequence similarity 131 member C
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM131C, family with sequence similarity 131 member C
  • Synonyms
    C1orf117
  • Links
    NCBI Gene ID: 348487
    UniProt: Q96AQ9

  • Chr Location
    1p36.13; chr1:16057769-16073651 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    3
  • Targeted
    3
  • Genomic Mutations
    3 involving Fam131c
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    10 strains or lines available
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000006218 Ensembl Gene Model | MGI Sequence Detail 15956 C57BL/6J ±  kb
transcript ENSMUST00000006380 Ensembl | MGI Sequence Detail 1433 Not Applicable  
polypeptide ENSMUSP00000006380 Ensembl | MGI Sequence Detail 273 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR026782 Protein FAM131
  • GlyGen
    A2ADB2 1 site
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 2
References
more
  • Summaries
    All 21
    Phenotypes 7
  • Earliest
    J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory