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Ctif Gene Detail
Summary
  • Symbol
    Ctif
  • Name
    CBP80/20-dependent translation initiation factor
  • Synonyms
    Gm672, LOC269037
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685518
    NCBI Gene: 269037
Location & Maps
more
  • Sequence Map
    Chr18:75431224-75697696 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      266473 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 51.06 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    CTIF, cap binding complex dependent translation initiation factor
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CTIF, cap binding complex dependent translation initiation factor
    Orthology source: HomoloGene
  • Synonyms
    Gm672, KIAA0427
  • Links
    NCBI Gene ID: 9811
    neXtProt AC: NX_O43310

  • Chr Location
    18q21.1; chr18:48539056-48863217 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    53
  • Gene trapped
    52
  • Transposon induced
    1
  • Genomic Mutations
    1 involving Ctif
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000052928 Ensembl Gene Model | MGI Sequence Detail 266473 C57BL/6J ±  kb
transcript ENSMUST00000165559 Ensembl | MGI Sequence Detail 6173 Not Applicable  
polypeptide ENSMUSP00000129974 Ensembl | MGI Sequence Detail 623 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    3523 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000030883 CBP80/20-dependent translation initiation factor
  • InterPro Domains
    IPR016024 Armadillo-type fold
    IPR016021 MIF4G-like domain
    IPR003890 MIF4G-like, type 3
Molecular
Reagents
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  • All nucleic 60
    cDNA 60

    Microarray probesets 1
References
more
  • Summaries
    All 23
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory