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Tmem132e Gene Detail
Summary
  • Symbol
    Tmem132e
  • Name
    transmembrane protein 132E
  • Synonyms
    LOC270893
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685490
    NCBI Gene: 270893
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:82279726-82337158 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 50.08 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    157 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685490
protein coding gene Chr11:82279281-82338447 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018827
protein coding gene Chr11:83643454-83702260 (+)
A/J MGP_AJ_G0018794
protein coding gene Chr11:80428497-80487128 (+)
AKR/J MGP_AKRJ_G0018764
protein coding gene Chr11:82829250-82890442 (+)
BALB/cJ MGP_BALBcJ_G0018767
protein coding gene Chr11:80830995-80888371 (+)
C3H/HeJ MGP_C3HHeJ_G0018581
protein coding gene Chr11:82882233-82943680 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019219
protein coding gene Chr11:86152695-86216253 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016853
protein coding gene Chr11:77394825-77452245 (+)
CAST/EiJ MGP_CASTEiJ_G0018136
protein coding gene Chr11:83444956-83507668 (+)
CBA/J MGP_CBAJ_G0018552
protein coding gene Chr11:89923844-89987119 (+)
DBA/2J MGP_DBA2J_G0018660
protein coding gene Chr11:79990841-80048831 (+)
FVB/NJ MGP_FVBNJ_G0018649
protein coding gene Chr11:79531619-79593202 (+)
LP/J MGP_LPJ_G0018730
protein coding gene Chr11:84169918-84231328 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018676
protein coding gene Chr11:90097435-90162457 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019259
protein coding gene Chr11:83092160-83152333 (+)
PWK/PhJ MGP_PWKPhJ_G0017906
protein coding gene Chr11:80823117-80885193 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017697
protein coding gene Chr11:82714147-82780006 (+)
WSB/EiJ MGP_WSBEiJ_G0018188
protein coding gene Chr11:82983405-83044622 (+)



Homology
more
  • Human Ortholog
    TMEM132E, transmembrane protein 132E
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM132E, transmembrane protein 132E
  • Synonyms
    DFNB99
  • Links
    NCBI Gene ID: 124842
    neXtProt AC: NX_Q6IEE7
    UniProt: Q6IEE7

  • Chr Location
    17q12; chr17:34580749-34639318 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human TMEM132E associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020701 Ensembl Gene Model | MGI Sequence Detail 57433 C57BL/6J ±  kb
transcript ENSMUST00000054245 Ensembl | MGI Sequence Detail 4386 Not Applicable  
polypeptide ENSMUSP00000052484 Ensembl | MGI Sequence Detail 1074 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 2
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:284992 Li J, et al., Whole-exome sequencing identifies a variant in TMEM132E causing autosomal-recessive nonsyndromic hearing loss DFNB99. Hum Mutat. 2015 Jan;36(1):98-105

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/14/2021
MGI 6.17
The Jackson Laboratory