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S100z Gene Detail
Summary
  • Symbol
    S100z
  • Name
    S100 calcium binding protein, zeta
  • Synonyms
    LOC268686
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685471
    NCBI Gene: 268686
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr13:95613809-95615163 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 13, 49.53 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    78 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685471
protein coding gene Chr13:95613776-95615229 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020841
protein coding gene Chr13:96957229-96958592 (-)
A/J MGP_AJ_G0020795
protein coding gene Chr13:93313916-93315295 (-)
AKR/J MGP_AKRJ_G0020769
protein coding gene Chr13:96166742-96168105 (-)
BALB/cJ MGP_BALBcJ_G0020792
protein coding gene Chr13:93990696-93992059 (-)
C3H/HeJ MGP_C3HHeJ_G0020585
protein coding gene Chr13:95857406-95858769 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021228
protein coding gene Chr13:99892358-99893712 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018797
protein coding gene Chr13:89142913-89144256 (-)
CAST/EiJ MGP_CASTEiJ_G0020104
protein coding gene Chr13:95157335-95158694 (-)
CBA/J MGP_CBAJ_G0020544
protein coding gene Chr13:103855879-103857242 (-)
DBA/2J MGP_DBA2J_G0020669
protein coding gene Chr13:93091549-93092912 (-)
FVB/NJ MGP_FVBNJ_G0020650
protein coding gene Chr13:91876489-91877852 (-)
LP/J MGP_LPJ_G0020744
protein coding gene Chr13:97063037-97064400 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020678
protein coding gene Chr13:104298187-104299541 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021268
protein coding gene Chr13:95560166-95561529 (-)
PWK/PhJ MGP_PWKPhJ_G0019856
protein coding gene Chr13:91871306-91872660 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019680
protein coding gene Chr13:91850527-91851869 (-)
WSB/EiJ MGP_WSBEiJ_G0020161
protein coding gene Chr13:96068313-96069676 (-)



Homology
more
  • Human Ortholog
    S100Z, S100 calcium binding protein Z
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    S100Z, S100 calcium binding protein Z
  • Synonyms
    Gm625, S100-zeta
  • Links
    NCBI Gene ID: 170591
    neXtProt AC: NX_Q8WXG8
    UniProt: Q8WXG8

  • Chr Location
    5q13.3; chr5:76850001-76952953 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 268686 NCBI Gene Model | MGI Sequence Detail 1355 C57BL/6J ±  kb
transcript NM_001081159 RefSeq | MGI Sequence Detail 300 Not Specified  
polypeptide NP_001074628 RefSeq | MGI Sequence Detail 99 Not Specified  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR018247 EF-Hand 1, calcium-binding site
    IPR002048 EF-hand domain
    IPR011992 EF-hand domain pair
    IPR013787 S100/CaBP-9k-type, calcium binding, subdomain
    IPR001751 S100/Calcium binding protein 7/8-like, conserved site
Molecular
Reagents
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  • All nucleic 1
    cDNA 1

    Microarray probesets 1
References
more
  • Summaries
    All 18
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:92488 Marenholz I, et al., S100 proteins in mouse and man: from evolution to function and pathology (including an update of the nomenclature). Biochem Biophys Res Commun. 2004 Oct 1;322(4):1111-22
  • Latest
    J:323263 Jonas W, et al., Identification of Novel Genes Involved in Hyperglycemia in Mice. Int J Mol Sci. 2022 Mar 16;23(6)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory