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Slc9c1
Gene Detail
 Symbol
Name
ID
Slc9c1
solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
MGI:2685456
Synonyms LOC208169, Slc9a10, spermNHE
Feature Type protein coding gene
Genetic Map
Chromosome 16
29.53 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr16:45535309-45607001 bp, + strand
From VEGA annotation of GRCm38

  71693 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:19505  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 dog

Gene Tree: Slc9c1

Human
homologs
Human Homolog SLC9C1, solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
NCBI Gene ID 285335
neXtProt AC  NX_Q4G0N8
Human Synonyms  NHE, SLC9A10, sperm-NHE
Human Chr (Location)  3q13.2; chr3:112140772-112294258 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from APF )
 
Homozygous null mice display male infertility and asthenozoospermia.
 
Interactions
Slc9c1 interacts with 102 markers (Mir1a-1, Mir1a-2, Mir18, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process cation transport, cell differentiation, ...
Component cell projection, cilium, ...
Function antiporter activity, solute:proton antiporter activity
External Resources: FuncBase
Expression
cDNA source data(2)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(3) cDNA(2) Other(1)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000034157 (Evidence)
Ensembl Gene ModelENSMUSG00000033210 (Evidence)
Entrez Gene208169 (Evidence)
UniGene277437
DFCITC1592336
DoTSDT.101188602, DT.101311188
NIA Mouse Gene IndexU017175
Consensus CDS ProjectCCDS28198.2
International Mouse Knockout Project StatusSlc9c1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034157 VEGA Gene Model | MGI Sequence Detail 71693 C57BL/6J ±  kb
transcript OTTMUST00000086549 VEGA | MGI Sequence Detail 3836 Not Applicable 
polypeptide OTTMUSP00000046874 VEGA | MGI Sequence Detail 1175 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(10) UniProt(4)
Polymorphisms SNPs within 2kb(779 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006153 Cation/H+ exchanger
InterPro IPR018422 Cation/H+ exchanger, CPA1 family
InterPro IPR000595 Cyclic nucleotide-binding domain
InterPro IPR018490 Cyclic nucleotide-binding-like
InterPro IPR014710 RmlC-like jelly roll fold
InterPro IPR027359 Voltage-dependent potassium channel, four helix bundle domain
Protein Ontology PR:000015211 sodium/hydrogen exchanger 10
References (Earliest) J:87248 Wang D, et al., A new sperm-specific Na+/H+ exchanger required for sperm motility and fertility. Nat Cell Biol. 2003 Dec;5(12):1117-22
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(25)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory