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Rimbp3
Gene Detail
Symbol

Name
ID
Rimbp3
RIMS binding protein 3
MGI:2685449
Synonyms
LOC239731, LOC385766, RIM-BP3
Feature Type
protein coding gene
Genetic Map
Chromosome 16
10.67 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr16:17208135-17213921 bp, + strand
From VEGA annotation of GRCm38

  5787 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:77940  Vertebrate Homology Class
3 human; 1 mouse; 1 rat; 1 cattle; 1 dog

Gene Tree: Rimbp3

Human
homologs
Human Homolog RIMBP3, RIMS binding protein 3
NCBI Gene ID 85376
neXtProt AC  NX_Q9UFD9
Human Synonyms  RIM-BP3, RIM-BP3.1, RIMBP3.1, RIMBP3A, RIM-BP3.A
Human Chr (Location)  chr22:18606124-18611919 (-)  GRCh38
Human Homolog RIMBP3B, RIMS binding protein 3B
NCBI Gene ID 440804
neXtProt AC  NX_A6NNM3
Human Synonyms  RIM-BP3.2, RIMBP3.2, RIM-BP3.B
Human Chr (Location)  22q11.21; chr22:21383751-21389169 (+)  GRCh38
Human Homolog RIMBP3C, RIMS binding protein 3C
NCBI Gene ID 150221
neXtProt AC  NX_A6NJZ7
Human Synonyms  RIM-BP3.3, RIMBP3.3
Human Chr (Location)  22q11.21; chr22:21545666-21551461 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(4) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Male mice homozygous for a null mutation display infertility with impaired spermiogenesis and defects in sperm head and flagellum morphology.
 
Interactions
Rimbp3 interacts with 122 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (1 annotations)
Component nucleus
External Resources: FuncBase
Expression
cDNA source data(15)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(15) cDNA(15)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000024840 (Evidence)
Ensembl Gene ModelENSMUSG00000071636 (Evidence)
Entrez Gene239731 (Evidence)
UniGene86671
DFCITC1678243, TC1585587
DoTSDT.101133506, DT.60100952
NIA Mouse Gene IndexU016864
Consensus CDS ProjectCCDS27998.2
International Mouse Knockout Project StatusRimbp3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024840 VEGA Gene Model | MGI Sequence Detail 5787 C57BL/6J ±  kb
transcript OTTMUST00000061191 VEGA | MGI Sequence Detail 5787 Not Applicable 
polypeptide OTTMUSP00000029961 VEGA | MGI Sequence Detail 1606 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(17 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003961 Fibronectin, type III
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR001452 Src homology-3 domain
InterPro IPR011511 Variant SH3
Protein Ontology PR:000033320 RIMS-binding protein 3
References
(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:144218 Zhou J, et al., RIM-BP3 is a manchette-associated protein essential for spermiogenesis. Development. 2009 Feb;136(3):373-82
All references(24)
Other
accession IDs
MGI:2686605

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory