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Rimbp3
Gene Detail
Symbol

Name
ID
Rimbp3
RIMS binding protein 3
MGI:2685449
Synonyms
LOC239731, LOC385766, RIM-BP3
Feature Type
protein coding gene
Genetic Map
Chromosome 16
10.67 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr16:17208135-17213921 bp, + strand
From VEGA annotation of GRCm38

  5787 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:77940  Vertebrate Homology Class
3 human; 1 mouse; 1 rat; 1 cattle; 1 dog

HCOP human homology predictions: RIMBP3, RIMBP3B, RIMBP3C
Gene Tree: Rimbp3

Human
homologs
RIMBP3, RIMS binding protein 3
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 85376
neXtProt AC: NX_Q9UFD9

Human Synonyms: RIM-BP3, RIM-BP3.1, RIMBP3.1, RIMBP3A, RIM-BP3.A

Human Chr (Location): chr22:18606124-18611919 (-)  GRCh38.p2

  2 More Homolog(s):
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(4) Targeted(1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Male mice homozygous for a null mutation display infertility with impaired spermiogenesis and defects in sperm head and flagellum morphology.
 
Interactions
Rimbp3 interacts with 122 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process fertilization, spermatid development
Component manchette, nucleus
Function protein binding
External Resources: FuncBase
Expression
cDNA source data(15)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(15) cDNA(15)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000024840 (Evidence)
Ensembl Gene Model ENSMUSG00000071636 (Evidence)
Entrez Gene 239731 (Evidence)
UniGene 86671
DFCI TC1585587, TC1678243
DoTS DT.101133506, DT.60100952
NIA Mouse Gene Index U016864
Consensus CDS Project CCDS27998.2
International Mouse Phenotyping Consortium Status Rimbp3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024840 VEGA Gene Model | MGI Sequence Detail 5787 C57BL/6J ±  kb
transcript OTTMUST00000061191 VEGA | MGI Sequence Detail 5787 Not Applicable 
polypeptide OTTMUSP00000029961 VEGA | MGI Sequence Detail 1606 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(17 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003961 Fibronectin, type III
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR001452 Src homology-3 domain
InterPro IPR011511 Variant SH3
Protein Ontology PR:000033320 RIMS-binding protein 3
References
(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:144218 Zhou J, et al., RIM-BP3 is a manchette-associated protein essential for spermiogenesis. Development. 2009 Feb;136(3):373-82
All references(23)
Other
accession IDs
MGI:2686605

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory