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Slc38a8 Gene Detail
Summary
  • Symbol
    Slc38a8
  • Name
    solute carrier family 38, member 8
  • Synonyms
    LOC234788
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685433
    NCBI Gene: 234788
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:120206341-120228437 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 67.80 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    57 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685433
protein coding gene Chr8:120206313-120228437 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034183
protein coding gene Chr8:122793093-122828666 (-)
A/J MGP_AJ_G0034163
protein coding gene Chr8:117751037-117774976 (-)
AKR/J MGP_AKRJ_G0034090
protein coding gene Chr8:121165751-121189593 (-)
BALB/cJ MGP_BALBcJ_G0034157
protein coding gene Chr8:117953261-117977356 (-)
C3H/HeJ MGP_C3HHeJ_G0033868
protein coding gene Chr8:121898658-121921753 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034677
protein coding gene Chr8:126908369-126944422 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031619
protein coding gene Chr8:110642234-110664511 (-)
CAST/EiJ MGP_CASTEiJ_G0033195
protein coding gene Chr8:121837690-121861545 (-)
CBA/J MGP_CBAJ_G0033841
protein coding gene Chr8:131523712-131554805 (-)
DBA/2J MGP_DBA2J_G0033997
protein coding gene Chr8:116973717-116996215 (-)
FVB/NJ MGP_FVBNJ_G0033940
protein coding gene Chr8:115999619-116021352 (-)
LP/J MGP_LPJ_G0034086
protein coding gene Chr8:122945516-122972628 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033987
protein coding gene Chr8:133979967-134001751 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034695
protein coding gene Chr8:121316613-121343369 (-)
PWK/PhJ MGP_PWKPhJ_G0032897
protein coding gene Chr8:116724914-116747770 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032737
protein coding gene Chr8:120020316-120043406 (-)
WSB/EiJ MGP_WSBEiJ_G0033311
protein coding gene Chr8:122034973-122060331 (-)



Homology
more
  • Human Ortholog
    SLC38A8, solute carrier family 38 member 8
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC38A8, solute carrier family 38 member 8
  • Synonyms
    FVH2
  • Links
    NCBI Gene ID: 146167
    neXtProt AC: NX_A6NNN8
    UniProt: A6NNN8

  • Chr Location
    16q23.3; chr16:84009667-84043372 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034224 Ensembl Gene Model | MGI Sequence Detail 22097 C57BL/6J ±  kb
transcript ENSMUST00000036748 Ensembl | MGI Sequence Detail 2623 Not Applicable  
polypeptide ENSMUSP00000038438 Ensembl | MGI Sequence Detail 432 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000032502 putative sodium-coupled neutral amino acid transporter 8
  • InterPro Domains
    IPR013057 Amino acid transporter, transmembrane domain
Molecular
Reagents
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  • All nucleic 13
    cDNA 12
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 21
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/14/2021
MGI 6.17
The Jackson Laboratory