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Ajap1 Gene Detail
Summary
  • Symbol
    Ajap1
  • Name
    adherens junction associated protein 1
  • Synonyms
    LOC230959
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685419
    NCBI Gene: 230959
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:153373221-153482811 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 83.71 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    514 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685419
protein coding gene Chr4:153373221-153485578 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029184
protein coding gene Chr4:157568737-157683103 (-)
A/J MGP_AJ_G0029149
protein coding gene Chr4:150960377-151077781 (-)
AKR/J MGP_AKRJ_G0029097
protein coding gene Chr4:155082326-155201015 (-)
BALB/cJ MGP_BALBcJ_G0029165
protein coding gene Chr4:151433880-151545902 (-)
C3H/HeJ MGP_C3HHeJ_G0028886
protein coding gene Chr4:155618177-155739233 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029614
protein coding gene Chr4:163237893-163351641 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026860
protein coding gene Chr4:143282539-143391598 (-)
CAST/EiJ MGP_CASTEiJ_G0028299
protein coding gene Chr4:152996196-153115252 (-)
CBA/J MGP_CBAJ_G0028848
protein coding gene Chr4:168129588-168265732 (-)
DBA/2J MGP_DBA2J_G0028997
protein coding gene Chr4:150989848-151103388 (-)
FVB/NJ MGP_FVBNJ_G0028961
protein coding gene Chr4:150177933-150290848 (-)
LP/J MGP_LPJ_G0029087
protein coding gene Chr4:157494726-157612643 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028988
protein coding gene Chr4:171040569-171170457 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029646
protein coding gene Chr4:155635530-155750866 (-)
PWK/PhJ MGP_PWKPhJ_G0028019
protein coding gene Chr4:146905840-147185310 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027853
protein coding gene Chr4:149913244-150027048 (-)
WSB/EiJ MGP_WSBEiJ_G0028379
protein coding gene Chr4:155797320-155909229 (-)



Homology
more
  • Human Ortholog
    AJAP1, adherens junctions associated protein 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    AJAP1, adherens junctions associated protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MOT8, SHREW1, SHREW-1
  • Links
    NCBI Gene ID: 55966
    neXtProt AC: NX_Q9UKB5
    UniProt: Q9UKB5

  • Chr Location
    1p36.32; chr1:4654775-4792518 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000039546 Ensembl Gene Model | MGI Sequence Detail 109591 C57BL/6J ±  kb
    transcript ENSMUST00000105646 Ensembl | MGI Sequence Detail 3048 Not Applicable  
    polypeptide ENSMUSP00000101271 Ensembl | MGI Sequence Detail 412 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 4
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 5
      Gene Ontology 4
      Phenotypes 8
    • Earliest
      J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
    • Latest
      J:237197 Klemmt PA, et al., Alternative exon usage creates novel transcript variants of tumor suppressor SHREW-1 gene with differential tissue expression profile. Biol Open. 2016 Nov 15;5(11):1607-1619

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory