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Usp49 Gene Detail
Summary
  • Symbol
    Usp49
  • Name
    ubiquitin specific peptidase 49
  • Synonyms
    C330046L10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685391
    NCBI Gene: 224836
Location & Maps
more
  • Sequence Map
    Chr17:47630690-47686738 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      56049 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 23.72 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    USP49, ubiquitin specific peptidase 49
  • Vertebrate Orthologs
    10
  • Human Ortholog
    USP49, ubiquitin specific peptidase 49
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 25862
    neXtProt AC: NX_Q70CQ1

  • Chr Location
    6p21; chr6:41789896-41895361 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 10235
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: USP49
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018349 VEGA Gene Model | MGI Sequence Detail 56049 C57BL/6J ±  kb
transcript OTTMUST00000044313 VEGA | MGI Sequence Detail 8252 Not Applicable  
polypeptide OTTMUSP00000019909 VEGA | MGI Sequence Detail 685 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    138 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000017188 ubiquitin carboxyl-terminal hydrolase 49
  • EC
  • InterPro Domains
    IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
    IPR018200 Ubiquitin specific protease, conserved site
    IPR028889 Ubiquitin specific protease domain
    IPR013083 Zinc finger, RING/FYVE/PHD-type
    IPR001607 Zinc finger, UBP-type
Molecular
Reagents
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  • All nucleic 45
    cDNA 45

    Microarray probesets 2
References
more
  • Summaries
    All 22
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory