Gm527 Gene Detail

Summary

• Symbol
  Gm527
• Name
  predicted gene 527
• Synonyms
  LOC217648

• Feature Type
  protein coding gene
• IDs
  MGI:2685373
  NCBI Gene: 217648
• Alliance
  gene page
• Transcription Start Sites
  4 TSS

Location &
Maps

• Sequence Map
  Chr12:64964685-64971365 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 12, 27.21 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  63 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2685373	protein coding gene	Chr12:64964680-64971366 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0019775	protein coding gene	Chr12:64383271-64389938 (+)
A/J	MGP_AJ_G0019734	protein coding gene	Chr12:62019932-62025593 (+)
AKR/J	MGP_AKRJ_G0019709	protein coding gene	Chr12:63986821-63993501 (+)
BALB/cJ	MGP_BALBcJ_G0019714	protein coding gene	Chr12:62463215-62469882 (+)
C3H/HeJ	MGP_C3HHeJ_G0019519	protein coding gene	Chr12:64337125-64343792 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0020166	protein coding gene	Chr12:66420543-66427223 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0017786	protein coding gene	Chr12:59834951-59841828 (+)
CAST/EiJ	MGP_CASTEiJ_G0019071	protein coding gene	Chr12:59037996-59044695 (+)
CBA/J	MGP_CBAJ_G0019488	protein coding gene	Chr12:68848939-68855606 (+)
DBA/2J	MGP_DBA2J_G0019604	protein coding gene	Chr12:61944609-61951289 (+)
FVB/NJ	MGP_FVBNJ_G0019592	protein coding gene	Chr12:60972244-60978949 (+)
LP/J	MGP_LPJ_G0019676	protein coding gene	Chr12:64411007-64417674 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0019630	protein coding gene	Chr12:71690698-71697365 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0020200	protein coding gene	Chr12:63389195-63393175 (+)
PWK/PhJ	MGP_PWKPhJ_G0018837	protein coding gene	Chr12:56219965-56226822 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0018631	protein coding gene	Chr12:57703408-57711793 (+)
WSB/EiJ	MGP_WSBEiJ_G0019122	protein coding gene	Chr12:63907420-63914092 (+)

Homology

• Human Ortholog
  C14orf28, chromosome 14 open reading frame 28

• Vertebrate Orthologs
  2

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  C14orf28, chromosome 14 open reading frame 28
  
• Synonyms
  c14_5270, DRIP1, DRIP-1
• Links
  HGNC:19834

  NCBI Gene ID: 122525

  neXtProt AC: NX_Q4W4Y0

  UniProt: Q4W4Y0

  
  
• Chr Location
  14q21.2; chr14:44897304-44907257 (+)  GRCh38.p7

---

• Alliance of Genome Resources
  Gm527 stringent orthology
  1 human;1 mouse;1 zebrafish
  
• HCOP
  vertebrate homology predictions: C14orf28
• Gene Tree
  Gm527
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  3 phenotype references
  

• All Mutations and Alleles
  2
• Chemically induced (other)
  1
• Targeted
  1
• Genomic Mutations
  1 involving Gm527
• Find Mice (IMSR)
  5 strains or lines available

Expression

• Assay Results
  672
• cDNA Data
  12

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Interactions

• Gm527 interacts with 132 markers (Mir1b, Mir7-1, Mir30c-1, ...) View All

Sequences &
Gene Models

• All Sequences
  34
• RefSeq
  2
• UniProt
  3
• CCDS
  CCDS56841.1

• Ensembl
  ENSMUSG00000047227 (Evidence)
• NCBI Gene
  217648

Representative Sequences			Length	Strain/Species
genomic	217648	NCBI Gene Model | MGI Sequence Detail	6681	C57BL/6J
transcript	NM_001025605	RefSeq | MGI Sequence Detail	1491	Not Specified
polypeptide	Q4KL13	UniProt | EBI | MGI Sequence Detail	310	Not Applicable

Protein
Information

• UniProt
  3 Sequences
• InterPro Domains
  IPR040029 Uncharacterized protein C14orf28-like

Molecular
Reagents

• All nucleic 12

  cDNA 12

  
  

  Microarray probesets 2

References

• Summaries
  All 16

  Phenotypes 3
• Earliest
  J:23389 Roderick TH, Using inversions to detect and study recessive lethals and detrimentals in mice, in Utilization of Mammalian Specific Locus Studies in Hazard Evaluation and Estimation of Genetic Risk. 1983:135-67.
• Latest
  J:57747 MGI Genome Annotation Group and UniGene Staff, MGI-UniGene Interconnection Effort. Database Download. 2015;

TSS for Gm527:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr113591	Chr12:64964612-64964644 (+)	-57 bp
Tssr113592	Chr12:64964675-64964718 (+)	12 bp
Tssr113593	Chr12:64964719-64964763 (+)	56 bp
Tssr113594	Chr12:64964765-64964775 (+)	85 bp