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Gm527 Gene Detail
Summary
  • Symbol
    Gm527
  • Name
    predicted gene 527
  • Synonyms
    LOC217648
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685373
    NCBI Gene: 217648
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:64964685-64971365 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 27.21 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    234 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685373
 protein coding gene Chr12:64964680-64971366 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019775
 protein coding gene Chr12:64383271-64389938 (+)
A/J MGP_AJ_G0019734
 protein coding gene Chr12:62019932-62025593 (+)
AKR/J MGP_AKRJ_G0019709
 protein coding gene Chr12:63986821-63993501 (+)
BALB/cJ MGP_BALBcJ_G0019714
 protein coding gene Chr12:62463215-62469882 (+)
C3H/HeJ MGP_C3HHeJ_G0019519
 protein coding gene Chr12:64337125-64343792 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020166
 protein coding gene Chr12:66420543-66427223 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017786
 protein coding gene Chr12:59834951-59841828 (+)
CAST/EiJ MGP_CASTEiJ_G0019071
 protein coding gene Chr12:59037996-59044695 (+)
CBA/J MGP_CBAJ_G0019488
 protein coding gene Chr12:68848939-68855606 (+)
DBA/2J MGP_DBA2J_G0019604
 protein coding gene Chr12:61944609-61951289 (+)
FVB/NJ MGP_FVBNJ_G0019592
 protein coding gene Chr12:60972244-60978949 (+)
LP/J MGP_LPJ_G0019676
 protein coding gene Chr12:64411007-64417674 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019630
 protein coding gene Chr12:71690698-71697365 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020200
 protein coding gene Chr12:63389195-63393175 (+)
PWK/PhJ MGP_PWKPhJ_G0018837
 protein coding gene Chr12:56219965-56226822 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018631
 protein coding gene Chr12:57703408-57711793 (+)
WSB/EiJ MGP_WSBEiJ_G0019122
 protein coding gene Chr12:63907420-63914092 (+)



Homology
more
  • Human Ortholog
    DORIP1, dopamine receptor interacting protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DORIP1, dopamine receptor interacting protein 1
  • Synonyms
    c14_5270, C14orf28, DRIP-1, DRIP1
  • Links
    NCBI Gene ID: 122525
    UniProt: Q4W4Y0

  • Chr Location
    14q21.2; chr14:44897275-44907257 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Targeted
    1
  • Genomic Mutations
    1 involving Gm527
  • Find Mice (IMSR)
    10 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    12
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 217648 NCBI Gene Model | MGI Sequence Detail 6681 C57BL/6J ±  kb
transcript NM_001025605 RefSeq | MGI Sequence Detail 1491 Not Specified  
polypeptide Q4KL13 UniProt | EBI | MGI Sequence Detail 310 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 2
References
more
  • Summaries
    All 20
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:344895 Jia J, et al., Gm527 deficiency in dentate gyrus improves memory through upregulating dopamine D1 receptor pathway. CNS Neurosci Ther. 2023 Nov;29(11):3290-3306
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory