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Mctp2 Gene Detail
Summary
  • Symbol
    Mctp2
  • Name
    multiple C2 domains, transmembrane 2
  • Synonyms
    LOC244049
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685335
    NCBI Gene: 244049
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:71727578-71956356 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 41.23 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    7020 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685335
 protein coding gene Chr7:71727575-71956850 (-)
129S1/SvImJ ENSMUSG00200011685
 protein coding gene Chr7:58487076-58668930 (-)
A/J ENSMUSG00195013820
 protein coding gene Chr7:62886468-63068350 (-)
AKR/J ENSMUSG00220019613
 protein coding gene Chr7:56419473-56601346 (-)
BALB/cJ ENSMUSG00180004232
 protein coding gene Chr7:59596192-59778069 (-)
C3H/HeJ ENSMUSG00175021140
 protein coding gene Chr7:60388352-60570197 (-)
C57BL/6NJ ENSMUSG00215014879
 protein coding gene Chr7:59506451-59688285 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029858
 protein coding gene Chr7:74667848-74895987 (-)
CAST/EiJ ENSTCUG00005003986
 protein coding gene Chr7:63056372-63240654 (-)
CBA/J ENSMUSG00210019809
 protein coding gene Chr7:60248392-60430244 (-)
DBA/2J ENSMUSG00185000929
 protein coding gene Chr7:64581828-64775310 (-)
FVB/NJ ENSMUSG00205017599
 protein coding gene Chr7:60212446-60391713 (-)
JF1/MsJ ENSUMUG00000005976
 protein coding gene Chr7:69318977-69503119 (-)
LP/J ENSMUSG00230011464
 protein coding gene Chr7:70656010-70837885 (-)
NOD/ShiLtJ ENSMUSG00190007105
 protein coding gene Chr7:60336487-60515733 (-)
NZO/HlLtJ ENSMUSG00225015852
 protein coding gene Chr7:68917677-69148722 (-)
PWK/PhJ ENSLUMG00010018185
 protein coding gene Chr7:58850903-59036236 (-)
SPRET/EiJ ENSMSPG00010003066
 protein coding gene Chr7:59234729-59463722 (-)
WSB/EiJ ENSIUOG00005020328
 protein coding gene Chr7:60738730-60920423 (-)



Homology
more
  • Human Ortholog
    MCTP2, multiple C2 and transmembrane domain containing 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MCTP2, multiple C2 and transmembrane domain containing 2
  • Links
    NCBI Gene ID: 55784
    UniProt: Q6DN12

  • Chr Location
    15q26.2; chr15:94231366-94483952 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    15
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032776 Ensembl Gene Model | MGI Sequence Detail 228779 C57BL/6J ±  kb
transcript ENSMUST00000079323 Ensembl | MGI Sequence Detail 5802 Not Applicable  
polypeptide ENSMUSP00000078302 Ensembl | MGI Sequence Detail 878 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000029624 multiple C2 and transmembrane domain-containing protein 2
    (term hierarchy)
  • InterPro Domains
    IPR000008 C2 domain
    IPR035892 C2 domain superfamily
    IPR013583 Multiple C2 domain and Transmembrane region Proteins, C-terminal
  • GlyGen
    Q5RJH2 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 2
References
more
  • Summaries
    All 41
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 17
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory