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Mctp2 Gene Detail
Summary
  • Symbol
    Mctp2
  • Name
    multiple C2 domains, transmembrane 2
  • Synonyms
    LOC244049
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685335
    NCBI Gene: 244049
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:72077830-72306608 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 41.23 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1216 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685335
protein coding gene Chr7:72077827-72307116 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032367
protein coding gene Chr7:73594376-73837809 (-)
A/J MGP_AJ_G0032346
protein coding gene Chr7:71958636-72192482 (-)
AKR/J MGP_AKRJ_G0032282
protein coding gene Chr7:73478668-73709372 (-)
BALB/cJ MGP_BALBcJ_G0032358
protein coding gene Chr7:71705680-71949814 (-)
C3H/HeJ MGP_C3HHeJ_G0032071
protein coding gene Chr7:74212846-74465643 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032850
protein coding gene Chr7:76608253-76862871 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029858
protein coding gene Chr7:74667848-74895987 (-)
CAST/EiJ MGP_CASTEiJ_G0031399
protein coding gene Chr7:65023594-65291565 (-)
CBA/J MGP_CBAJ_G0032037
protein coding gene Chr7:79056274-79326231 (-)
DBA/2J MGP_DBA2J_G0032192
protein coding gene Chr7:70648752-70888555 (-)
FVB/NJ MGP_FVBNJ_G0032147
protein coding gene Chr7:70723015-70949440 (-)
LP/J MGP_LPJ_G0032273
protein coding gene Chr7:74798180-75055033 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032184
protein coding gene Chr7:79311554-79558524 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032868
protein coding gene Chr7:72910733-73157838 (-)
PWK/PhJ MGP_PWKPhJ_G0031119
protein coding gene Chr7:63768465-64008260 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030960
protein coding gene Chr7:59941754-60204257 (-)
WSB/EiJ MGP_WSBEiJ_G0031517
protein coding gene Chr7:73263380-73517852 (-)



Homology
more
  • Human Ortholog
    MCTP2, multiple C2 and transmembrane domain containing 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MCTP2, multiple C2 and transmembrane domain containing 2
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 55784
    neXtProt AC: NX_Q6DN12
    UniProt: Q6DN12

  • Chr Location
    15q26.2; chr15:94231184-94483952 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 69254
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MCTP2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032776 Ensembl Gene Model | MGI Sequence Detail 228779 C57BL/6J ±  kb
transcript ENSMUST00000079323 Ensembl | MGI Sequence Detail 5802 Not Applicable  
polypeptide ENSMUSP00000078302 Ensembl | MGI Sequence Detail 878 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 2
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 13
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:284228 Ikegami K, et al., Effect of expression alteration in flanking genes on phenotypes of St8sia2-deficient mice. Sci Rep. 2019 Sep 20;9(1):13634

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory