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Ntn5 Gene Detail
Summary
  • Symbol
    Ntn5
  • Name
    netrin 5
  • Synonyms
    LOC243967
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685330
    NCBI Gene: 243967
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:45684022-45694556 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 29.43 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    112 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685330
protein coding gene Chr7:45684022-45694556 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032239
protein coding gene Chr7:45988346-45998926 (+)
A/J MGP_AJ_G0032218
protein coding gene Chr7:45079907-45090537 (+)
AKR/J MGP_AKRJ_G0032154
protein coding gene Chr7:46327070-46337604 (+)
BALB/cJ MGP_BALBcJ_G0032230
protein coding gene Chr7:45073314-45083944 (+)
C3H/HeJ MGP_C3HHeJ_G0031945
protein coding gene Chr7:46824397-46835461 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032722
protein coding gene Chr7:48240566-48251100 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029736
protein coding gene Chr7:47634903-47645404 (+)
CAST/EiJ MGP_CASTEiJ_G0031274
protein coding gene Chr7:38262765-38273335 (+)
CBA/J MGP_CBAJ_G0031910
protein coding gene Chr7:49846635-49857169 (+)
DBA/2J MGP_DBA2J_G0032068
protein coding gene Chr7:44757517-44768097 (+)
FVB/NJ MGP_FVBNJ_G0032019
protein coding gene Chr7:44532556-44543090 (+)
LP/J MGP_LPJ_G0032146
protein coding gene Chr7:46695154-46705664 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032056
protein coding gene Chr7:48531021-48541555 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032738
protein coding gene Chr7:45542143-45552773 (+)
PWK/PhJ MGP_PWKPhJ_G0030996
protein coding gene Chr7:38125911-38136514 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030834
protein coding gene Chr7:33568002-33578503 (+)
WSB/EiJ MGP_WSBEiJ_G0031391
protein coding gene Chr7:46047286-46057817 (+)



Homology
more
  • Human Ortholog
    NTN5, netrin 5
  • Vertebrate Orthologs
    6
  • Human Ortholog
    NTN5, netrin 5
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 126147
    neXtProt AC: NX_Q8WTR8
    UniProt: Q8WTR8

  • Chr Location
    19q13.33; chr19:48661407-48673119 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit ectopic motor neurons that migrate out of the ventral horn and into the motor roots.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 243967 NCBI Gene Model | MGI Sequence Detail 10535 C57BL/6J ±  kb
transcript NM_001358870 RefSeq | MGI Sequence Detail 2157 C57BL/6  
polypeptide Q3UQ22 UniProt | EBI | MGI Sequence Detail 452 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 3
    Primer pair 2
    Other 2

    Microarray probesets 2
References
more
  • Summaries
    All 19
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:227617 Garrett AM, et al., Analysis of Expression Pattern and Genetic Deletion of Netrin5 in the Developing Mouse. Front Mol Neurosci. 2016;9:3

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
05/14/2019
MGI 6.14
The Jackson Laboratory