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Vwde Gene Detail
Summary
  • Symbol
    Vwde
  • Name
    von Willebrand factor D and EGF domains
  • Synonyms
    LOC232585
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685313
    NCBI Gene: 232585
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr6:13185610-13224965 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 5.64 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    226 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685313
protein coding gene Chr6:13156299-13224965 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030458
protein coding gene Chr6:10233948-10310865 (-)
A/J MGP_AJ_G0030431
protein coding gene Chr6:9842519-9909463 (-)
AKR/J MGP_AKRJ_G0030358
protein coding gene Chr6:10186036-10254612 (-)
BALB/cJ MGP_BALBcJ_G0030440
protein coding gene Chr6:9836864-9920780 (-)
C3H/HeJ MGP_C3HHeJ_G0030154
protein coding gene Chr6:10103267-10176172 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030895
protein coding gene Chr6:10673076-10747727 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028106
protein coding gene Chr6:9087549-9157809 (-)
CAST/EiJ MGP_CASTEiJ_G0029556
protein coding gene Chr6:9969033-10040543 (-)
CBA/J MGP_CBAJ_G0030132
protein coding gene Chr6:10869878-10983722 (-)
DBA/2J MGP_DBA2J_G0030276
protein coding gene Chr6:9769526-9841895 (-)
FVB/NJ MGP_FVBNJ_G0030230
protein coding gene Chr6:9675272-9744026 (-)
LP/J MGP_LPJ_G0030363
protein coding gene Chr6:10191395-10278208 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030266
protein coding gene Chr6:11618162-11710932 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030925
protein coding gene Chr6:10065520-10134217 (-)
PWK/PhJ MGP_PWKPhJ_G0029270
protein coding gene Chr6:9524636-9594488 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029106
protein coding gene Chr6:9985140-10055633 (-)
WSB/EiJ MGP_WSBEiJ_G0029632
protein coding gene Chr6:9996864-10077157 (-)



Homology
more
  • Human Ortholog
    VWDE, von Willebrand factor D and EGF domains
  • Vertebrate Orthologs
    10
  • Human Ortholog
    VWDE, von Willebrand factor D and EGF domains
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 221806
    neXtProt AC: NX_Q8N2E2
    UniProt: Q8N2E2

  • Chr Location
    7p21.3; chr7:12330883-12404226 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 35456
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: VWDE
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 232585 NCBI Gene Model | MGI Sequence Detail 39356 C57BL/6J ±  kb
transcript NM_001368871 RefSeq | MGI Sequence Detail 5485 C57BL/6  
polypeptide Q6DFV8 UniProt | EBI | MGI Sequence Detail 926 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • InterPro Domains
    IPR018097 EGF-like calcium-binding, conserved site
    IPR001881 EGF-like calcium-binding domain
    IPR013032 EGF-like, conserved site
    IPR000742 EGF-like domain
    IPR008979 Galactose-binding-like domain superfamily
    IPR009030 Growth factor receptor cysteine-rich domain superfamily
    IPR001846 von Willebrand factor, type D domain
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 1
References
more
  • Summaries
    All 12
    Gene Ontology 1
  • Earliest
    J:23000 MGD Nomenclature Committee, 2/14/1995;
  • Latest
    J:57747 MGI Genome Annotation Group and UniGene Staff, MGI-UniGene Interconnection Effort. Database Download. 2015;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory