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Col28a1 Gene Detail
Summary
  • Symbol
    Col28a1
  • Name
    collagen, type XXVIII, alpha 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685312
    NCBI Gene: 213945
  • Gene Overview
    MyGene.info: COL28A1
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr6:7997808-8192617 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 3.44 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2372 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685312
protein coding gene Chr6:7997100-8193709 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030446
protein coding gene Chr6:4880666-5067180 (-)
A/J MGP_AJ_G0030419
protein coding gene Chr6:4746729-4926853 (-)
AKR/J MGP_AKRJ_G0030346
protein coding gene Chr6:4910393-5097244 (-)
BALB/cJ MGP_BALBcJ_G0030428
protein coding gene Chr6:4715071-4908769 (-)
C3H/HeJ MGP_C3HHeJ_G0030142
protein coding gene Chr6:4806124-5004631 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030883
protein coding gene Chr6:5051467-5256761 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028094
protein coding gene Chr6:4268748-4451362 (-)
CAST/EiJ MGP_CASTEiJ_G0029543
protein coding gene Chr6:4785331-4993456 (-)
CBA/J MGP_CBAJ_G0030120
protein coding gene Chr6:5185178-5401507 (-)
DBA/2J MGP_DBA2J_G0030264
protein coding gene Chr6:4681731-4855822 (-)
FVB/NJ MGP_FVBNJ_G0030218
protein coding gene Chr6:4666876-4833827 (-)
LP/J MGP_LPJ_G0030351
protein coding gene Chr6:4873017-5078365 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030254
protein coding gene Chr6:5272453-5480483 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030913
protein coding gene Chr6:4815592-4992576 (-)
PWK/PhJ MGP_PWKPhJ_G0029258
protein coding gene Chr6:4563187-4746474 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029094
protein coding gene Chr6:4849235-5032973 (-)
WSB/EiJ MGP_WSBEiJ_G0029620
protein coding gene Chr6:4780692-4976636 (-)



Homology
more
  • Human Ortholog
    COL28A1, collagen type XXVIII alpha 1 chain
  • Vertebrate Orthologs
    8
  • Human Ortholog
    COL28A1, collagen type XXVIII alpha 1 chain
    Orthology source: HGNC, HomoloGene
  • Synonyms
    COL28
  • Links
    NCBI Gene ID: 340267
    neXtProt AC: NX_Q2UY09
    UniProt: Q2UY09

  • Chr Location
    7p21.3; chr7:7338543-7542062 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000068794 Ensembl Gene Model | MGI Sequence Detail 194810 C57BL/6J ±  kb
transcript ENSMUST00000115537 Ensembl | MGI Sequence Detail 4230 Not Applicable  
polypeptide ENSMUSP00000111199 Ensembl | MGI Sequence Detail 1141 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000005711 collagen alpha-1(XXVIII) chain
  • InterPro Domains
    IPR008160 Collagen triple helix repeat
    IPR002223 Pancreatic trypsin inhibitor Kunitz domain
    IPR036880 Pancreatic trypsin inhibitor Kunitz domain superfamily
    IPR020901 Proteinase inhibitor I2, Kunitz, conserved site
    IPR036465 von Willebrand factor A-like domain superfamily
    IPR002035 von Willebrand factor, type A
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 21
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 3
  • Earliest
    J:108496 Veit G, et al., Collagen XXVIII, a novel von Willebrand factor A domain-containing protein with many imperfections in the collagenous domain. J Biol Chem. 2006 Feb 10;281(6):3494-504
  • Latest
    J:265607 Naba A, et al., Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression. Sci Rep. 2017 Jan 10;7:40495

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory