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H1fx Gene Detail
Summary
  • Symbol
    H1fx
  • Name
    H1 histone family, member X
  • Synonyms
    H1X, LOC243529
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685307
    NCBI Gene: 243529
  • Gene Overview
    MyGene.info: H1FX
Location & Maps
more
  • Sequence Map
    Chr6:87980421-87981637 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      1217 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 39.13 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    H1FX, H1 histone family member X
  • Vertebrate Orthologs
    7
  • Human Ortholog
    H1FX, H1 histone family member X
    Orthology source: HomoloGene, HGNC
  • Synonyms
    H1.10, H1X
  • Links
    NCBI Gene ID: 8971
    neXtProt AC: NX_Q92522

  • Chr Location
    3q21.3; chr3:129314771-129316277 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    4
  • Gene trapped
    1
  • Spontaneous
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving H1fx
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Other Mouse Links
  • Other Vertebrate Links
    Xenbase h1fx
    ZFIN h1fx
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024647 VEGA Gene Model | MGI Sequence Detail 1217 C57BL/6J ±  kb
transcript OTTMUST00000060595 VEGA | MGI Sequence Detail 1217 Not Applicable  
polypeptide OTTMUSP00000029567 VEGA | MGI Sequence Detail 188 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    4 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR005819 Histone H5
    IPR005818 Linker histone H1/H5, domain H15
    IPR011991 Winged helix-turn-helix DNA-binding domain
Molecular
Reagents
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  • All nucleic 1
    cDNA 1

    Microarray probesets 2
References
more
  • Summaries
    All 23
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:141291 Tamplin OJ, et al., Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives. BMC Genomics. 2008;9(1):511
  • Latest
    J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory