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Garem2 Gene Detail
Summary
  • Symbol
    Garem2
  • Name
    GRB2 associated regulator of MAPK1 subtype 2
  • Synonyms
    Fam59b, Gareml, LOC242915
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685290
    NCBI Gene: 242915
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:30105196-30118380 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 15.92 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    49 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685290
protein coding gene Chr5:30105161-30118380 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029383
protein coding gene Chr5:28088732-28101868 (+)
A/J MGP_AJ_G0029349
protein coding gene Chr5:27149796-27163053 (+)
AKR/J MGP_AKRJ_G0029300
protein coding gene Chr5:28234663-28247799 (+)
BALB/cJ MGP_BALBcJ_G0029360
protein coding gene Chr5:27679548-27692809 (+)
C3H/HeJ MGP_C3HHeJ_G0029081
protein coding gene Chr5:28264871-28278112 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029813
protein coding gene Chr5:29805433-29818679 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027051
protein coding gene Chr5:24670763-24683973 (+)
CAST/EiJ MGP_CASTEiJ_G0028492
protein coding gene Chr5:27368448-27381642 (+)
CBA/J MGP_CBAJ_G0029049
protein coding gene Chr5:30356448-30369703 (+)
DBA/2J MGP_DBA2J_G0029198
protein coding gene Chr5:27355077-27368340 (+)
FVB/NJ MGP_FVBNJ_G0029156
protein coding gene Chr5:26756122-26770782 (+)
LP/J MGP_LPJ_G0029283
protein coding gene Chr5:28535898-28549034 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029185
protein coding gene Chr5:31306878-31320102 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029847
protein coding gene Chr5:27797974-27812198 (+)
PWK/PhJ MGP_PWKPhJ_G0028216
protein coding gene Chr5:26464741-26478079 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028047
protein coding gene Chr5:27142222-27155471 (+)
WSB/EiJ MGP_WSBEiJ_G0028572
protein coding gene Chr5:27874775-27888885 (+)



Homology
more
  • Human Ortholog
    GAREM2, GRB2 associated regulator of MAPK1 subtype 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GAREM2, GRB2 associated regulator of MAPK1 subtype 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FAM59B, GAREML
  • Links
    NCBI Gene ID: 150946
    neXtProt AC: NX_Q75VX8
    UniProt: Q75VX8

  • Chr Location
    2p23.3; chr2:26173091-26202405 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 19063
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: GAREM2
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    22 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    2
  • Radiation induced
    3
  • Spontaneous
    1
  • Targeted
    2
  • Genomic Mutations
    6 involving Garem2
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 242915 NCBI Gene Model | MGI Sequence Detail 13185 C57BL/6J ±  kb
transcript NM_001167879 RefSeq | MGI Sequence Detail 3832 C57BL/6  
polypeptide Q6PAJ3 UniProt | EBI | MGI Sequence Detail 880 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 3
References
more
  • Summaries
    All 40
    Diseases 1
    Phenotypes 22
  • Earliest
    J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/11/2019
MGI 6.14
The Jackson Laboratory