A3galt2
Gene Detail

Symbol Name ID

A3galt2 alpha 1,3-galactosyltransferase 2 (isoglobotriaosylceramide synthase) MGI:2685279

Synonyms

iGb3, LOC215493

Feature Type

protein coding gene

Genetic Map

Chromosome 4

62.23 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr4:128755364-128769298 bp, + strand From VEGA annotation of GRCm38   13935 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:16326  Vertebrate Homology Class
1 mouse; 1 rat; 1 rhesus macaque; 1 dog

Protein SuperFamily: histo-blood group 1 transferase
Gene Tree: A3galt2

Alleles and phenotypes

All alleles(4) : Targeted(4)
 

Mice homozygous for a knock-out allele are viable, fertile and behaviorally normal with no detectable alterations in the development and function of invariant natural killer T cells.

 

Gene Ontology (GO) classifications

All GO classifications: (11 annotations)

Process	carbohydrate metabolic process, glycosphingolipid biosynthetic process
Component	Golgi apparatus, membrane
Function	alpha-1,3-galactosyltransferase activity, metal ion binding, ...

External Resources: FuncBase

Expression

cDNA source data(2)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(4) cDNA(2) Other(2)
Microarray probesets(1)

Other database links

VEGA Gene Model	OTTMUSG00000009545 (Evidence)
Ensembl Gene Model	ENSMUSG00000028794 (Evidence)
Entrez Gene	215493 (Evidence)
UniGene	300900
DoTS	DT.94178244
NIA Mouse Gene Index	U004851
EC	2.4.1.87
Consensus CDS Project	CCDS18675.1
International Mouse Knockout Project Status	A3galt2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000009545	VEGA Gene Model | MGI Sequence Detail	13935	C57BL/6J
transcript	OTTMUST00000068218	VEGA | MGI Sequence Detail	3390	Not Applicable
polypeptide	OTTMUSP00000034432	VEGA | MGI Sequence Detail	370	Not Applicable

All sequences(20) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(67 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR005076	Glycosyl transferase, family 6
Protein Ontology	PR:000003515	alpha-1,3-galactosyltransferase 2

References

(Earliest) J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
(Latest) J:189359 Porubsky S, et al., Globosides but not isoglobosides can impact the development of invariant NKT cells and their interaction with dendritic cells. J Immunol. 2012 Sep 15;189(6):3007-17
All references(32)