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Hdx Gene Detail
Summary
  • Symbol
    Hdx
  • Name
    highly divergent homeobox
  • Synonyms
    D030011N01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685226
    NCBI Gene: 245596
Location & Maps
more
  • Sequence Map
    ChrX:111569931-111697079 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      127149 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome X, 48.29 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    HDX, highly divergent homeobox
  • Vertebrate Orthologs
    9
  • Human Ortholog
    HDX, highly divergent homeobox
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CXorf43, D030011N01Rik
  • Links
    NCBI Gene ID: 139324
    neXtProt AC: NX_Q7Z353

  • Chr Location
    Xq21.1; chrX:84317874-84502584 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 16963
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: HDX
  • Gene Tree
    Hdx
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 images
    8 phenotype references
  • All Mutations and Alleles
    5
  • Gene trapped
    2
  • Targeted
    3
  • Incidental Mutations
    APF
Male chimeras hemizygous for a gene trapped allele appear normal at E9.5.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018434 VEGA Gene Model | MGI Sequence Detail 127149 C57BL/6J ±  kb
transcript OTTMUST00000044483 VEGA | MGI Sequence Detail 9534 Not Applicable  
polypeptide OTTMUSP00000019993 VEGA | MGI Sequence Detail 692 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    227 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 2
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory