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Ldoc1
Gene Detail
Symbol

Name
ID
Ldoc1
leucine zipper, down-regulated in cancer 1
MGI:2685212
Synonyms
LOC245441, Mar7, Mart7
Feature Type
protein coding gene
Genetic Map
Chromosome X
34.57 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
ChrX:61709497-61710955 bp, + strand
From VEGA annotation of GRCm38

  1459 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32153  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: LDOC1
Gene Tree: Ldoc1

Human
homologs
LDOC1, leucine zipper, down-regulated in cancer 1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 23641
neXtProt AC: NX_O95751

Human Synonyms: BCUR1, Mar7, Mart7

Human Chr (Location): Xq27; chrX:141175745-141177214 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from APF )
Interactions
Ldoc1 interacts with 168 markers (Mir1a-1, Mir1a-2, Mir10a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process negative regulation of cell proliferation
Component nucleolus, nucleus
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (30)    Tissues (19)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 30
cDNA source data(18)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(19) cDNA(18) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000017589 (Evidence)
Ensembl Gene Model ENSMUSG00000057615 (Evidence)
Entrez Gene 434784 (Evidence)
UniGene 23468
DFCI TC1584735
DoTS DT.60103365
Consensus CDS Project CCDS30163.1
International Mouse Phenotyping Consortium Status Ldoc1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017589 VEGA Gene Model | MGI Sequence Detail 1459 C57BL/6J ±  kb
transcript OTTMUST00000042760 VEGA | MGI Sequence Detail 1459 Not Applicable 
polypeptide OTTMUSP00000019208 VEGA | MGI Sequence Detail 151 Not Applicable 

For the selected sequences
All sequences(16) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(5 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000009746 protein LDOC1
References
(Earliest) J:96508 Brandt J, et al., Transposable elements as a source of genetic innovation: expression and evolution of a family of retrotransposon-derived neogenes in mammals. Gene. 2005 Jan 17;345(1):101-11
(Latest) J:220468 Walentin K, et al., A Grhl2-dependent gene network controls trophoblast branching morphogenesis. Development. 2015 Mar 15;142(6):1125-36
All references(26)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory