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Ldoc1 Gene Detail
Summary
  • Symbol
    Ldoc1
  • Name
    regulator of NFKB signaling
  • Synonyms
    LOC245441, Mar7, Mart7, Rtl7, Sirh7
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685212
    NCBI Gene: 434784
  • Gene Overview
    MyGene.info: LDOC1
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:61709616-61710950 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 34.57 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    5 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685212
protein coding gene ChrX:61709497-61710955 (.)
129S1/SvImJ MGP_129S1SvImJ_G0035761
protein coding gene ChrX:57119009-57120467 (+)
A/J MGP_AJ_G0035743
protein coding gene ChrX:57332050-57333508 (+)
AKR/J MGP_AKRJ_G0035663
protein coding gene ChrX:58870507-58871965 (+)
BALB/cJ MGP_BALBcJ_G0035730
protein coding gene ChrX:56648413-56649871 (+)
C3H/HeJ MGP_C3HHeJ_G0035432
protein coding gene ChrX:57671908-57673366 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036259
protein coding gene ChrX:58675118-58676576 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033111
protein coding gene ChrX:57042345-57043814 (+)
CAST/EiJ MGP_CASTEiJ_G0034725
protein coding gene ChrX:43400014-43401473 (+)
CBA/J MGP_CBAJ_G0035407
protein coding gene ChrX:60416020-60417478 (+)
DBA/2J MGP_DBA2J_G0035561
protein coding gene ChrX:56877635-56879093 (+)
FVB/NJ MGP_FVBNJ_G0035511
protein coding gene ChrX:56398155-56399613 (+)
LP/J MGP_LPJ_G0035649
protein coding gene ChrX:57713354-57714812 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035547
protein coding gene ChrX:62026257-62027715 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036275
protein coding gene ChrX:57146942-57148400 (+)
PWK/PhJ MGP_PWKPhJ_G0034420
protein coding gene ChrX:41551900-41553364 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034264
protein coding gene ChrX:44287857-44289308 (+)
WSB/EiJ MGP_WSBEiJ_G0034868
protein coding gene ChrX:56586581-56588039 (+)



Homology
more
  • Human Ortholog
    LDOC1, LDOC1, regulator of NFKB signaling
  • Vertebrate Orthologs
    7
  • Human Ortholog
    LDOC1, LDOC1, regulator of NFKB signaling
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BCUR1, Mar7, Mart7, RTL7, SIRH7
  • Links
    NCBI Gene ID: 23641
    neXtProt AC: NX_O95751
    UniProt: O95751

  • Chr Location
    Xq27.1; chrX:141175745-141177214 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 434784 NCBI Gene Model | MGI Sequence Detail 1335 C57BL/6J ±  kb
transcript NM_001018087 RefSeq | MGI Sequence Detail 1390 C57BL/6  
polypeptide Q7TPY9 UniProt | EBI | MGI Sequence Detail 151 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 19
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 26
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:96508 Brandt J, et al., Transposable elements as a source of genetic innovation: expression and evolution of a family of retrotransposon-derived neogenes in mammals. Gene. 2005 Jan 17;345(1):101-11
  • Latest
    J:220468 Walentin K, et al., A Grhl2-dependent gene network controls trophoblast branching morphogenesis. Development. 2015 Mar 15;142(6):1125-36

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory