Dusp5
Gene Detail

Symbol Name ID

Dusp5 dual specificity phosphatase 5 MGI:2685183

Synonyms

LOC240672

Feature Type

protein coding gene

Genetic Map

Chromosome 19

47.98 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr19:53529109-53542431 bp, + strand From VEGA annotation of GRCm38   13323 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:3256  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: dual specificity protein phosphatase (MAP kinase phosphatase)
Gene Tree: Dusp5

Human homologs

Human Homolog		DUSP5, dual specificity phosphatase 5
NCBI Gene ID		1847
neXtProt AC		NX_Q16690
Human Synonyms		DUSP, HVH3
Human Chr (Location)		10q25; chr10:112257625-112271302 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (14 annotations)

Process	dephosphorylation, endoderm formation, ...
Component	nucleoplasm
Function	hydrolase activity, MAP kinase tyrosine/serine/threonine phosphatase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (75)    Tissues (15)    Images (20)
Theiler Stages: 23, 24, 26, 28

Assay Type	Results
RNA in situ	75

cDNA source data(4)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress

Molecular reagents

All nucleic(5) cDNA(5)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000029765 (Evidence)
Ensembl Gene Model	ENSMUSG00000034765 (Evidence)
Entrez Gene	240672 (Evidence)
DFCI	TC1755372
DoTS	DT.528745
NIA Mouse Gene Index	U019572
EC	3.1.3.16, 3.1.3.48
Consensus CDS Project	CCDS38024.1
International Mouse Knockout Project Status	Dusp5

Sequences

Length	Strain/Species
genomic	OTTMUSG00000029765	VEGA Gene Model | MGI Sequence Detail	13323	C57BL/6J
transcript	OTTMUST00000073872	VEGA | MGI Sequence Detail	2473	Not Applicable
polypeptide	OTTMUSP00000038291	VEGA | MGI Sequence Detail	384	Not Applicable

All sequences(16) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(51 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR024950	Dual specificity phosphatase
InterPro	IPR000340	Dual specificity phosphatase, catalytic domain
InterPro	IPR020422	Dual specificity phosphatase, subgroup, catalytic domain
InterPro	IPR008343	Mitogen-activated protein (MAP) kinase phosphatase
InterPro	IPR000387	Protein-tyrosine/Dual specificity phosphatase
InterPro	IPR016130	Protein-tyrosine phosphatase, active site
InterPro	IPR001763	Rhodanese-like domain
Protein Ontology	PR:000006755	dual specificity protein phosphatase 5

References

(Earliest) J:93300 Blackshaw S, et al., Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)