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Dusp5
Gene Detail
Symbol

Name
ID
Dusp5
dual specificity phosphatase 5
MGI:2685183
Synonyms
LOC240672
Feature Type
protein coding gene
Genetic Map
Chromosome 19
47.98 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr19:53529109-53542431 bp, + strand
From VEGA annotation of GRCm38

  13323 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3256  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: DUSP5
Protein SuperFamily: dual specificity protein phosphatase (MAP kinase phosphatase)
Gene Tree: Dusp5

Human
homologs
DUSP5, dual specificity phosphatase 5
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 1847
neXtProt AC: NX_Q16690

Human Synonyms: DUSP, HVH3

Human Chr (Location): 10q25; chr10:110497867-110511544 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from CvDC )
Interactions
Dusp5 interacts with 167 markers (Mir7-1, Mir16-1, Mir19a, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (4 records)
Data Summary: Results (75)    Tissues (15)    Images (20)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 75
cDNA source data(4)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase dusp5 ; ZFIN dusp5    NEW 
Molecular
reagents
All nucleic(5) cDNA(5)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000029765 (Evidence)
Ensembl Gene Model ENSMUSG00000034765 (Evidence)
Entrez Gene 240672 (Evidence)
DFCI TC1755372
DoTS DT.528745
NIA Mouse Gene Index U019572
EC 3.1.3.16, 3.1.3.48
Consensus CDS Project CCDS38024.1
International Mouse Phenotyping Consortium Status Dusp5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029765 VEGA Gene Model | MGI Sequence Detail 13323 C57BL/6J ±  kb
transcript OTTMUST00000073872 VEGA | MGI Sequence Detail 2473 Not Applicable 
polypeptide OTTMUSP00000038291 VEGA | MGI Sequence Detail 384 Not Applicable 

For the selected sequences
All sequences(16) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(57 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR024950 Dual specificity phosphatase
InterPro IPR000340 Dual specificity phosphatase, catalytic domain
InterPro IPR020422 Dual specificity phosphatase, subgroup, catalytic domain
InterPro IPR008343 Mitogen-activated protein (MAP) kinase phosphatase
InterPro IPR000387 Protein-tyrosine/Dual specificity phosphatase
InterPro IPR016130 Protein-tyrosine phosphatase, active site
InterPro IPR001763 Rhodanese-like domain
Protein Ontology PR:000006755 dual specificity protein phosphatase 5
References
(Earliest) J:93300 Blackshaw S, et al., Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
(Latest) J:198483 Finelli MJ, et al., Differential phosphorylation of Smad1 integrates BMP and neurotrophin pathways through Erk/Dusp in axon development. Cell Rep. 2013 May 30;3(5):1592-606
All references(30)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory