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Lrrc30 Gene Detail
Summary
  • Symbol
    Lrrc30
  • Name
    leucine rich repeat containing 30
  • Synonyms
    LOC240131
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685172
    NCBI Gene: 240131
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:67937960-67939718 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 38.80 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    119 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685172
 protein coding gene Chr17:67937959-67939718 (-)
129S1/SvImJ ENSMUSG00200037999
 protein coding gene Chr17:63288096-63289855 (-)
A/J ENSMUSG00195015742
 protein coding gene Chr17:64630485-64632244 (-)
AKR/J ENSMUSG00220018469
 protein coding gene Chr17:63703011-63704770 (-)
BALB/cJ ENSMUSG00180017450
 protein coding gene Chr17:64367798-64369557 (-)
C3H/HeJ ENSMUSG00175029780
 protein coding gene Chr17:63675232-63676991 (-)
C57BL/6NJ ENSMUSG00215014030
 protein coding gene Chr17:63327861-63329620 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021842
 protein coding gene Chr17:63739187-63740941 (-)
CAST/EiJ ENSTCUG00005025545
 protein coding gene Chr17:64248391-64250149 (-)
CBA/J ENSMUSG00210028101
 protein coding gene Chr17:63475071-63476830 (-)
DBA/2J ENSMUSG00185022519
 protein coding gene Chr17:66319609-66321368 (-)
FVB/NJ ENSMUSG00205015909
 protein coding gene Chr17:64101358-64103117 (-)
JF1/MsJ ENSUMUG00000031640
 protein coding gene Chr17:65977694-65979452 (-)
LP/J ENSMUSG00230012238
 protein coding gene Chr17:67306277-67308036 (-)
NOD/ShiLtJ ENSMUSG00190029622
 protein coding gene Chr17:63458568-63460327 (-)
NZO/HlLtJ ENSMUSG00225025672
 protein coding gene Chr17:69586741-69588500 (-)
PWK/PhJ ENSLUMG00010026999
 protein coding gene Chr17:63246783-63248541 (-)
SPRET/EiJ ENSMSPG00010015885
 protein coding gene Chr17:63629297-63631059 (-)
WSB/EiJ ENSIUOG00005031708
 protein coding gene Chr17:64325471-64327230 (-)



Homology
more
  • Human Ortholog
    LRRC30, leucine rich repeat containing 30
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC30, leucine rich repeat containing 30
  • Links
    NCBI Gene ID: 339291
    UniProt: A6NM36

  • Chr Location
    18p11.23; chr18:7231089-7232044 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 240131 NCBI Gene Model | MGI Sequence Detail 1759 C57BL/6J ±  kb
    transcript NM_001033340 RefSeq | MGI Sequence Detail 1759 C57BL/6  
    polypeptide Q3UV48 UniProt | EBI | MGI Sequence Detail 300 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • Protein Ontology
      PR:000032265 leucine-rich repeat-containing protein 30
      (term hierarchy)
    • InterPro Domains
      IPR001611 Leucine-rich repeat
      IPR052595 Leucine-rich repeat-containing protein 69/Receptor-like
      IPR050216 Leucine-rich repeat domain-containing protein
      IPR032675 Leucine-rich repeat domain superfamily
      IPR003591 Leucine-rich repeat, typical subtype
    Molecular
    Reagents
    less
    • All nucleic 4
      cDNA 4

      Microarray probesets 2
    References
    more
    • Summaries
      All 21
      Gene Ontology 1
      Phenotypes 5
    • Earliest
      J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory