About   Help   FAQ
Olfm4 Gene Detail
Summary
  • Symbol
    Olfm4
  • Name
    olfactomedin 4
  • Synonyms
    GC1, GW112, LOC239192, LOC380924, OlfD, pPD4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685142
    NCBI Gene: 380924
Location & Maps
more
  • Sequence Map
    Chr14:80000302-80021930 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      21629 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 42.78 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    OLFM4, olfactomedin 4
  • Vertebrate Orthologs
    11
  • Human Ortholog
    OLFM4, olfactomedin 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    bA209J19.1, GC1, GW112, hGC-1, hOLfD, OlfD, OLM4, UNQ362
  • Links
    NCBI Gene ID: 10562
    neXtProt AC: NX_Q6UX06

  • Chr Location
    13q14.3; chr13:53028741-53052061 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Olfm4
  • Incidental Mutations
    APF , CvDC
Mice homozygous for a knock-out allele exhibit reduced colonization of the gastric mucosa by Helicobacter pylori but increased inflammatory response to H. pylori infection.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022026 Ensembl Gene Model | MGI Sequence Detail 21629 C57BL/6J ±  kb
transcript ENSMUST00000088735 Ensembl | MGI Sequence Detail 1640 Not Applicable  
polypeptide ENSMUSP00000086112 Ensembl | MGI Sequence Detail 538 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    88 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 9
    Primer pair 1
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2685759
References
more
  • Summaries
    All 31
    Developmental Gene Expression 6
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:90964 Rosenbauer F, et al., pDP4, a novel glycoprotein secreted by mature granulocytes, is regulated by transcription factor PU.1. Blood. 2004 Jun 1;103(11):4294-301
  • Latest
    J:230791 Liu W, et al., Olfactomedin 4 deletion induces colon adenocarcinoma in Apc mice. Oncogene. 2016 Mar 14;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/20/2016
MGI 6.05
The Jackson Laboratory