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Ccnb1ip1
Gene Detail
 Symbol
Name
ID
Ccnb1ip1
cyclin B1 interacting protein 1
MGI:2685134
Synonyms Hei10, LOC239083, mei4
Feature Type protein coding gene
Genetic Map
Chromosome 14
26.25 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr14:50789249-50795728 bp, - strand
From NCBI annotation of GRCm38

  6480 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:18819  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Gene Tree: Ccnb1ip1

Human
homologs
Human Homolog CCNB1IP1, cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
NCBI Gene ID 57820
neXtProt AC  NX_Q9NPC3
Human Synonyms  C14orf18, HEI10
Human Chr (Location)  14q11.2; chr14:20311368-20333312 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Chemically induced (ENU)(1) Gene trapped(3) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for an ENU-induced mutation have abnormal testicular and ovarian morphology and exhibit sterility in both sexes owing to meiotic defects.
 
Phenotype Images(1)
Interactions
Ccnb1ip1 interacts with 136 markers (Mir7-1, Mir16-1, Mir19a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (24 annotations)
Process blastocyst formation, chiasma assembly, ...
Component chromosome, nucleus, ...
Function coenzyme F420-0 gamma-glutamyl ligase activity, coenzyme F420-2 alpha-glutamyl ligase activity, ...
Expression
Literature Summary: (1 records)
Data Summary: Results (17)    Tissues (12)    Images (3)
Theiler Stages: 10, 18, 23, 25, 28
Assay TypeResults
RT-PCR 17
cDNA source data(7)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(9) cDNA(7) Primer pair(2)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000071470 (Evidence)
Entrez Gene239083 (Evidence)
UniGene343880
DFCITC1669685
DoTSDT.40181561
NIA Mouse Gene IndexU035513
EC6.3.2.-
Consensus CDS ProjectCCDS49477.1
International Mouse Knockout Project StatusCcnb1ip1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 239083 NCBI Gene Model | MGI Sequence Detail 6480 C57BL/6J ±  kb
transcript NM_001111119 RefSeq | MGI Sequence Detail 1508 C57BL/6 
polypeptide D3Z3K2 UniProt | EBI | MGI Sequence Detail 276 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(10) UniProt(1)
Polymorphisms SNPs within 2kb(83 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001841 Zinc finger, RING-type
Protein Ontology PR:000005117 E3 ubiquitin-protein ligase CCNB1IP1
Graphical View of Protein Domain Structure
References (Earliest) J:86161 Ward JO, et al., Toward the genetics of mammalian reproduction: induction and mapping of gametogenesis mutants in mice. Biol Reprod. 2003 Nov;69(5):1615-25
(Latest) J:205585 Qiao H, et al., Antagonistic roles of ubiquitin ligase HEI10 and SUMO ligase RNF212 regulate meiotic recombination. Nat Genet. 2014 Feb;46(2):194-9
All references(27)
Other
accession IDs
MGI:3050546

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory