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Nek10 Gene Detail
Summary
  • Symbol
    Nek10
  • Name
    NIMA (never in mitosis gene a)- related kinase 10
  • Synonyms
    LOC238944
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685128
    NCBI Gene: 674895
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr14:14803580-15012059 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 7.08 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2637 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685128
protein coding gene Chr14:14803415-15012059 (.)
129S1/SvImJ MGP_129S1SvImJ_G0021012
protein coding gene Chr14:7374461-7594654 (+)
A/J MGP_AJ_G0020960
protein coding gene Chr14:7175954-7368115 (+)
AKR/J MGP_AKRJ_G0020937
protein coding gene Chr14:7332283-7539968 (+)
BALB/cJ MGP_BALBcJ_G0020963
protein coding gene Chr14:7216512-7413797 (+)
C3H/HeJ MGP_C3HHeJ_G0020747
protein coding gene Chr14:7427170-7644126 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021396
protein coding gene Chr14:7563007-7796276 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018965
protein coding gene Chr14:7831531-8033750 (+)
CAST/EiJ MGP_CASTEiJ_G0020270
protein coding gene Chr14:7338868-7567338 (+)
CBA/J MGP_CBAJ_G0020713
protein coding gene Chr14:7853205-8129125 (+)
DBA/2J MGP_DBA2J_G0020837
protein coding gene Chr14:7083714-7300040 (+)
FVB/NJ MGP_FVBNJ_G0020819
protein coding gene Chr14:7011699-7199612 (+)
LP/J MGP_LPJ_G0020912
protein coding gene Chr14:7400713-7620299 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020845
protein coding gene Chr14:7917160-8126215 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021429
protein coding gene Chr14:7228118-7448513 (+)
PWK/PhJ MGP_PWKPhJ_G0020021
protein coding gene Chr14:7098500-7328692 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019841
protein coding gene Chr14:7384422-7813847 (+)
WSB/EiJ MGP_WSBEiJ_G0020327
protein coding gene Chr14:7264335-7492489 (+)



Homology
more
  • Human Ortholog
    NEK10, NIMA related kinase 10
  • Vertebrate Orthologs
    8
  • Human Ortholog
    NEK10, NIMA related kinase 10
    Orthology source: HGNC
  • Links
    NCBI Gene ID: 152110
    neXtProt AC: NX_Q6ZWH5
    UniProt: Q6ZWH5

  • Chr Location
    3p24.1; chr3:27107336-27369460 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 674895 NCBI Gene Model | MGI Sequence Detail 208480 C57BL/6J ±  kb
    transcript NM_001195229 RefSeq | MGI Sequence Detail 3348 C57BL/6  
    polypeptide Q3UGM2 UniProt | EBI | MGI Sequence Detail 1111 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 1
      cDNA 1
    References
    more
    • Summaries
      All 17
      Developmental Gene Expression 1
      Gene Ontology 2
      Phenotypes 5
    • Earliest
      J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
    • Latest
      J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.
    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory