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Eif4e1b Gene Detail
Summary
  • Symbol
    Eif4e1b
  • Name
    eukaryotic translation initiation factor 4E family member 1B
  • Synonyms
    Eif4eloo
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685119
    NCBI Gene: 218268
  • Gene Overview
    MyGene.info: EIF4E1B
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:54783998-54788459 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 29.39 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    12 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685119
protein coding gene Chr13:54783994-54788459 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020580
protein coding gene Chr13:54207248-54213541 (+)
A/J MGP_AJ_G0020534
protein coding gene Chr13:52211035-52215368 (+)
AKR/J MGP_AKRJ_G0020512
protein coding gene Chr13:53749149-53753537 (+)
BALB/cJ MGP_BALBcJ_G0020530
protein coding gene Chr13:52449554-52453896 (+)
C3H/HeJ MGP_C3HHeJ_G0020329
protein coding gene Chr13:53570018-53575304 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020964
protein coding gene Chr13:55864074-55868435 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018546
protein coding gene Chr13:50201689-50205907 (+)
CAST/EiJ MGP_CASTEiJ_G0019843
protein coding gene Chr13:53656577-53660979 (+)
CBA/J MGP_CBAJ_G0020289
protein coding gene Chr13:57986737-57991970 (+)
DBA/2J MGP_DBA2J_G0020412
protein coding gene Chr13:51777838-51782650 (+)
FVB/NJ MGP_FVBNJ_G0020391
protein coding gene Chr13:51237382-51259531 (+)
LP/J MGP_LPJ_G0020488
protein coding gene Chr13:54476761-54481125 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020419
protein coding gene Chr13:57469792-57473265 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021007
protein coding gene Chr13:53341894-53346203 (+)
PWK/PhJ MGP_PWKPhJ_G0019599
protein coding gene Chr13:51769775-51774743 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019426
protein coding gene Chr13:52264491-52273188 (+)
WSB/EiJ MGP_WSBEiJ_G0019905
protein coding gene Chr13:53675082-53680231 (+)



Homology
more
  • Human Ortholog
    EIF4E1B, eukaryotic translation initiation factor 4E family member 1B
  • Vertebrate Orthologs
    9
  • Human Ortholog
    EIF4E1B, eukaryotic translation initiation factor 4E family member 1B
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 253314
    neXtProt AC: NX_A6NMX2
    UniProt: A6NMX2

  • Chr Location
    5q35.2; chr5:176630613-176646644 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Targeted
    4
  • Genomic Mutations
    2 involving Eif4e1b
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000074895 Ensembl Gene Model | MGI Sequence Detail 4462 C57BL/6J ±  kb
transcript ENSMUST00000126785 Ensembl | MGI Sequence Detail 841 Not Applicable  
polypeptide ENSMUSP00000118697 Ensembl | MGI Sequence Detail 250 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    10 Sequences
  • Protein Ontology
    PR:000006991 eukaryotic translation initiation factor 4E type 1B
  • InterPro Domains
    IPR019770 Eukaryotic translation initiation factor 4E (eIF-4E), conserved site
    IPR001040 Translation Initiation factor eIF- 4e
    IPR023398 Translation Initiation factor eIF- 4e-like
Molecular
Reagents
less
  • All nucleic 7
    cDNA 6
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:3034242
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:190741 Migdalska AM, et al., Generation of the Sotos syndrome deletion in mice. Mamm Genome. 2012 Dec;23(11-12):749-57

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/26/2019
MGI 6.14
The Jackson Laboratory