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Syndig1l Gene Detail
Summary
  • Symbol
    Syndig1l
  • Name
    synapse differentiation inducing 1 like
  • Synonyms
    capucin, LOC238321, SynDIG2, Tmem90a
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685107
    NCBI Gene: 627191
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:84724051-84745605 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 39.33 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    685 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685107
 protein coding gene Chr12:84724051-84745720 (-)
129S1/SvImJ ENSMUSG00200047583
 protein coding gene Chr12:76738543-76760111 (-)
A/J ENSMUSG00195032882
 protein coding gene Chr12:79358081-79379637 (-)
AKR/J ENSMUSG00220045346
 protein coding gene Chr12:77153142-77174698 (-)
BALB/cJ ENSMUSG00180022131
 protein coding gene Chr12:78395893-78417448 (-)
C3H/HeJ ENSMUSG00175035269
 protein coding gene Chr12:81488988-81510541 (-)
C57BL/6NJ ENSMUSG00215044702
 protein coding gene Chr12:77702380-77723941 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017949
 protein coding gene Chr12:79065391-79087032 (-)
CAST/EiJ ENSTCUG00005030836
 protein coding gene Chr12:77674637-77696337 (-)
CBA/J ENSMUSG00210039545
 protein coding gene Chr12:77902231-77923787 (-)
DBA/2J ENSMUSG00185042774
 protein coding gene Chr12:79759432-79780989 (-)
FVB/NJ ENSMUSG00205035850
 protein coding gene Chr12:77570898-77592459 (-)
JF1/MsJ ENSUMUG00000023119
 protein coding gene Chr12:83755573-83777590 (-)
LP/J ENSMUSG00230045581
 protein coding gene Chr12:86821730-86843289 (-)
NOD/ShiLtJ ENSMUSG00190029778
 protein coding gene Chr12:76959215-76980772 (-)
NZO/HlLtJ ENSMUSG00225050582
 protein coding gene Chr12:88858793-88880347 (-)
PWK/PhJ ENSLUMG00010027752
 protein coding gene Chr12:77772485-77794429 (-)
SPRET/EiJ ENSMSPG00010019748
 protein coding gene Chr12:79592752-79613414 (-)
WSB/EiJ ENSIUOG00005040245
 protein coding gene Chr12:77588252-77616364 (-)



Homology
more
  • Human Ortholog
    SYNDIG1L, synapse differentiation inducing 1 like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SYNDIG1L, synapse differentiation inducing 1 like
  • Synonyms
    CAPUCIN, DSPC1, IFITMD4, SynDIG2, TMEM90A
  • Links
    NCBI Gene ID: 646658
    UniProt: A6NDD5

  • Chr Location
    14q24.3; chr14:74405894-74480143 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from multigenic genotypes
    12 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Targeted
    6
  • Genomic Mutations
    1 involving Syndig1l
  • Find Mice (IMSR)
    12 strains or lines available
Mice homozygous for a knock-out allele are viable and fertile, exhibit normal brain anatomy, and show no alterations in striatal vulnerability to a mutant huntingtin fragment.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    622
  • Tissues
    10
  • cDNA Data
    7
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000071234 Ensembl Gene Model | MGI Sequence Detail 21555 C57BL/6J ±  kb
transcript ENSMUST00000095550 Ensembl | MGI Sequence Detail 2524 Not Applicable  
polypeptide ENSMUSP00000093206 Ensembl | MGI Sequence Detail 237 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 7
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 39
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 12
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory