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Prss38
Gene Detail
Symbol

Name
ID
Prss38
protease, serine 38
MGI:2685095
Synonyms
Gm249, LOC216797
Feature Type
protein coding gene
Genetic Map
Chromosome 11
37.70 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:59372669-59375657 bp, - strand
From VEGA annotation of GRCm38

  2989 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:18831  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: PRSS38
Protein SuperFamily: trypsin
Gene Tree: Prss38

Human
homologs
PRSS38, protease, serine, 38
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 339501
neXtProt AC: NX_A1L453

Human Synonyms: MPN2

Human Chr (Location): 1q42.13; chr1:227815692-227860439 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Prss38 interacts with 36 markers (Mir18, Mir18b, Mir92-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process proteolysis
Component extracellular region
Function hydrolase activity, peptidase activity, ...
External Resources: FuncBase
Expression
cDNA source data(1)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(1) cDNA(1)
Microarray probesets(1)
Other database
links
VEGA Gene Model OTTMUSG00000005788 (Evidence)
Ensembl Gene Model ENSMUSG00000049291 (Evidence)
Entrez Gene 216797 (Evidence)
UniGene 339586
DFCI TC1616113
DoTS DT.101274753
NIA Mouse Gene Index U060092
EC 3.4.21.-
Consensus CDS Project CCDS36170.1
International Mouse Phenotyping Consortium Status Prss38
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005788 VEGA Gene Model | MGI Sequence Detail 2989 C57BL/6J ±  kb
transcript OTTMUST00000012810 VEGA | MGI Sequence Detail 1243 Not Applicable 
polypeptide OTTMUSP00000005954 VEGA | MGI Sequence Detail 322 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(5) UniProt(1)
Polymorphisms
SNPs within 2kb(37 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000010541 serine protease MPN2
References
(Earliest) J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(22)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory