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Prss38
Gene Detail
Symbol

Name
ID
Prss38
protease, serine 38
MGI:2685095
Synonyms
Gm249, LOC216797
Feature Type
protein coding gene
Genetic Map
Chromosome 11
37.70 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:59372669-59375657 bp, - strand
From VEGA annotation of GRCm38

  2989 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:18831  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: trypsin
Gene Tree: Prss38

Human
homologs
Human Homolog PRSS38, protease, serine, 38
NCBI Gene ID 339501
neXtProt AC  NX_A1L453
Human Synonyms  MPN2
Human Chr (Location)  1q42.13; chr1:227815717-227846470 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Prss38 interacts with 36 markers (Mir18, Mir18b, Mir92-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process proteolysis
Component extracellular region
Function catalytic activity, hydrolase activity, ...
External Resources: FuncBase
Expression
cDNA source data(1)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(1) cDNA(1)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000005788 (Evidence)
Ensembl Gene ModelENSMUSG00000049291 (Evidence)
Entrez Gene216797 (Evidence)
UniGene339586
DFCITC1616113
DoTSDT.101274753
NIA Mouse Gene IndexU060092
EC3.4.21.-
Consensus CDS ProjectCCDS36170.1
International Mouse Knockout Project StatusPrss38
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005788 VEGA Gene Model | MGI Sequence Detail 2989 C57BL/6J ±  kb
transcript OTTMUST00000012810 VEGA | MGI Sequence Detail 1243 Not Applicable 
polypeptide OTTMUSP00000005954 VEGA | MGI Sequence Detail 322 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(5) UniProt(1)
Polymorphisms
SNPs within 2kb(37 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000010541 serine protease MPN2
References
(Earliest) J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(23)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory