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Myrfl Gene Detail
Summary
  • Symbol
    Myrfl
  • Name
    myelin regulatory factor-like
  • Synonyms
    Gm239, LOC237558
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685085
    NCBI Gene: 237558
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:116776545-116896879 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 64.90 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1562 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685085
protein coding gene Chr10:116776535-116896919 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017747
protein coding gene Chr10:119577111-119699080 (-)
A/J MGP_AJ_G0017723
protein coding gene Chr10:114969378-115089602 (-)
AKR/J MGP_AKRJ_G0017685
protein coding gene Chr10:118297095-118420309 (-)
BALB/cJ MGP_BALBcJ_G0017686
protein coding gene Chr10:115367531-115488330 (-)
C3H/HeJ MGP_C3HHeJ_G0017511
protein coding gene Chr10:118534684-118658088 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018143
protein coding gene Chr10:123736111-123864260 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015823
protein coding gene Chr10:109559492-109679939 (-)
CAST/EiJ MGP_CASTEiJ_G0017073
protein coding gene Chr10:118827977-118961384 (-)
CBA/J MGP_CBAJ_G0017480
protein coding gene Chr10:128585301-128735536 (-)
DBA/2J MGP_DBA2J_G0017585
protein coding gene Chr10:114108107-114229582 (-)
FVB/NJ MGP_FVBNJ_G0017580
protein coding gene Chr10:113060440-113182285 (-)
LP/J MGP_LPJ_G0017660
protein coding gene Chr10:120163286-120291519 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017609
protein coding gene Chr10:131474198-131608559 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018181
protein coding gene Chr10:118374663-118499839 (-)
PWK/PhJ MGP_PWKPhJ_G0016855
protein coding gene Chr10:114161733-114332217 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016645
protein coding gene Chr10:117182052-117312048 (-)
WSB/EiJ MGP_WSBEiJ_G0017133
protein coding gene Chr10:118557824-118695766 (-)



Homology
more
  • Human Ortholog
    MYRFL, myelin regulatory factor like
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MYRFL, myelin regulatory factor like
    Orthology source: HomoloGene, HGNC
  • Synonyms
    bcm1377, C12orf15, C12orf28
  • Links
    NCBI Gene ID: 196446
    neXtProt AC: NX_Q96LU7
    UniProt: Q96LU7

  • Chr Location
    12q15; chr12:69824518-69958726 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 88588
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MYRFL
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 237558 NCBI Gene Model | MGI Sequence Detail 120335 C57BL/6J ±  kb
transcript NM_001033333 RefSeq | MGI Sequence Detail 3114 C57BL/6  
polypeptide Q3UN70 UniProt | EBI | MGI Sequence Detail 904 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR030392 Intramolecular chaperone auto-processing domain
    IPR026932 Myelin gene regulatory factor C-terminal domain 1
    IPR025719 Myelin gene regulatory factor C-terminal domain 2
    IPR024061 NDT80 DNA-binding domain
    IPR008967 p53-like transcription factor, DNA-binding
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 2
References
more
  • Summaries
    All 28
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/16/2019
MGI 6.13
The Jackson Laboratory