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Myrfl Gene Detail
Summary
  • Symbol
    Myrfl
  • Name
    myelin regulatory factor-like
  • Synonyms
    Gm239, LOC237558
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685085
    NCBI Gene: 237558
Location & Maps
more
  • Sequence Map
    Chr10:116776545-116896879 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      120335 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 64.90 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    MYRFL, myelin regulatory factor-like
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MYRFL, myelin regulatory factor-like
    Orthology source: HGNC, HomoloGene
  • Synonyms
    bcm1377, C12orf15, C12orf28
  • Links
    NCBI Gene ID: 196446
    neXtProt AC: NX_Q96LU7

  • Chr Location
    12q15; chr12:69824569-69958724 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 88588
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: MYRFL
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Targeted
    5
  • Genomic Mutations
    1 involving Myrfl
  • Incidental Mutations
    APF , CvDC
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 237558 NCBI Gene Model | MGI Sequence Detail 120335 C57BL/6J ±  kb
transcript NM_001033333 RefSeq | MGI Sequence Detail 3114 C57BL/6  
polypeptide Q3UN70 UniProt | EBI | MGI Sequence Detail 904 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1562 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR030392 Intramolecular chaperone auto-processing domain
    IPR026932 Myelin gene regulatory factor C-terminal domain 1
    IPR025719 Myelin gene regulatory factor C-terminal domain 2
    IPR024061 NDT80 DNA-binding domain
    IPR008967 p53-like transcription factor, DNA-binding
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 2
References
more
  • Summaries
    All 23
    Gene Ontology 2
    Phenotypes 12
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory