Gpr55
Gene Detail

Symbol Name ID

Gpr55 G protein-coupled receptor 55 MGI:2685064

Synonyms

LOC227326

Feature Type

protein coding gene

Genetic Map

Chromosome 1

43.94 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr1:85939537-85961055 bp, - strand From NCBI annotation of GRCm38   21519 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Mammalian homology

human; rat; cattle; chimpanzee; dog, domestic    (Mammalian Orthology)
Comparative Map (Mouse/Human Gpr55 ± 2 cM)

Protein SuperFamily: probable G protein-coupled receptor 55
Gene Tree: Gpr55

Human ortholog

GPR55 G protein-coupled receptor 55 NCBI Gene ID 9290
Human Chr2:231772043-231789941 bp, - strand Reference GRCh37.p2 Primary Assembly

Alleles and phenotypes

All alleles(5) : Targeted(5)
 

Mice homozygous for a knock-out allele exhibit increased bone volume due to impaired osteoclast function in male mice. Female mice exhibit a milder phenotype.

 

Gene Ontology (GO) classifications

All GO classifications: (18 annotations)

Process	activation of phospholipase C activity, bone resorption, ...
Component	integral to membrane, integral to plasma membrane, ...
Function	cannabinoid receptor activity, G-protein coupled receptor activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
cDNA source data(5)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(5) cDNA(5)
Microarray probesets(1)

Other database links

Ensembl Gene Model	ENSMUSG00000049608 (Evidence)
Entrez Gene	227326 (Evidence)
UniGene	244158
DFCI	TC1590505
DoTS	DT.101340096
NIA Mouse Gene Index	U050777
Consensus CDS Project	CCDS15115.1
International Mouse Knockout Project Status	Gpr55

Sequences

Length	Strain/Species
genomic	227326	NCBI Gene Model | MGI Sequence Detail	21519	C57BL/6J
transcript	NM_001033290	RefSeq | MGI Sequence Detail	2550	C57BL/6
polypeptide	Q3UJF0	UniProt | EBI | MGI Sequence Detail	327	Not Applicable

All sequences(17) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(138 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000276	GPCR, rhodopsin-like
InterPro	IPR017452	GPCR, rhodopsin-like, 7TM
Protein Ontology	PR:000001534	G-protein coupled receptor 55

Graphical View of Protein Domain Structure

References

(Earliest) J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(27)