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Hmcn1
Gene Detail
Symbol

Name
ID
Hmcn1
hemicentin 1
MGI:2685047
Synonyms
EG545370, LOC240793
Feature Type
protein coding gene
Genetic Map
Chromosome 1
63.84 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:150562524-150993435 bp, - strand
From VEGA annotation of GRCm38

  430912 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23741  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Hmcn1

Human
homologs
Human Homolog HMCN1, hemicentin 1
NCBI Gene ID 83872
neXtProt AC  NX_Q96RW7
Human Synonyms  ARMD1, FBLN6, FIBL6, FIBL-6
Human Chr (Location)  1q25.3-q31.1; chr1:185734551-186190953 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human HMCN1
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Hmcn1 interacts with 78 markers (Mir1a-1, Mir1a-2, Mir29b-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process biological_process
Component basement membrane, cell cortex, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (7)    Tissues (7)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 7
cDNA source data(27)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(29) cDNA(27) Primer pair(2)
Microarray probesets(78)
Other database
links
VEGA Gene ModelOTTMUSG00000021664 (Evidence)
Ensembl Gene ModelENSMUSG00000066842 (Evidence)
Entrez Gene545370 (Evidence)
UniGene379425
DFCITC1619487, TC1604028
DoTSDT.91407270, DT.101703333
NIA Mouse Gene IndexU021876
Consensus CDS ProjectCCDS15357.2
International Mouse Knockout Project StatusHmcn1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021664 VEGA Gene Model | MGI Sequence Detail 430912 C57BL/6J ±  kb
transcript OTTMUST00000051425 VEGA | MGI Sequence Detail 17908 Not Applicable 
polypeptide OTTMUSP00000024195 VEGA | MGI Sequence Detail 5634 Not Applicable 

For the selected sequences
All sequences(47) RefSeq(8) UniProt(8)
Polymorphisms
SNPs within 2kb(5181 from dbSNP Build 137)    SNPs within 2kb including multiple locations(5183)
Protein-related
information
ResourceIDDescription
InterPro IPR026823 Complement Clr-like EGF domain
InterPro IPR001881 EGF-like calcium-binding
InterPro IPR018097 EGF-like calcium-binding, conserved site
InterPro IPR013032 EGF-like, conserved site
InterPro IPR000152 EGF-type aspartate/asparagine hydroxylation site
InterPro IPR000742 Epidermal growth factor-like domain
InterPro IPR006605 G2 nidogen/fibulin G2F
InterPro IPR009017 Green fluorescent protein
InterPro IPR023413 Green fluorescent protein-like
InterPro IPR013098 Immunoglobulin I-set
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003598 Immunoglobulin subtype 2
InterPro IPR009030 Insulin-like growth factor binding protein, N-terminal
InterPro IPR000884 Thrombospondin, type 1 repeat
InterPro IPR002035 von Willebrand factor, type A
Protein Ontology PR:000008624 hemicentin-1
References
(Earliest) J:123065 Xu X, et al., Hemicentins assemble on diverse epithelia in the mouse. J Histochem Cytochem. 2007 Feb;55(2):119-26
(Latest) J:192188 Zhao Y, et al., Cross-reactivity of anti-programmed death ligand 2 polyclonal antibody in mouse tissues. Sci China Life Sci. 2012 Nov;55(11):940-7
All references(27)
Other
accession IDs
MGI:3646881

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory