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Hmcn1 Gene Detail
Summary
  • Symbol
    Hmcn1
  • Name
    hemicentin 1
  • Synonyms
    EG545370, LOC240793
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685047
    NCBI Gene: 545370
  • Gene Overview
    MyGene.info: HMCN1
Location & Maps
more
  • Sequence Map
    Chr1:150562524-150993435 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      430912 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    HMCN1, hemicentin 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    HMCN1, hemicentin 1
    Orthology source: HomoloGene
  • Synonyms
    ARMD1, FBLN6, FIBL6, FIBL-6
  • Links
    NCBI Gene ID: 83872
    neXtProt AC: NX_Q96RW7

  • Chr Location
    1q25.3-q31.1; chr1:185734381-186190953 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human HMCN1 associations

Human Disease Mouse Models
       Macular Degeneration, Age-Related, 1; ARMD1   OMIM: 603075
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    2
  • Targeted
    3
  • Genomic Mutations
    2 involving Hmcn1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021664 VEGA Gene Model | MGI Sequence Detail 430912 C57BL/6J ±  kb
transcript OTTMUST00000051425 VEGA | MGI Sequence Detail 17908 Not Applicable  
polypeptide OTTMUSP00000024195 VEGA | MGI Sequence Detail 5634 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    5168 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 29
    cDNA 27
    Primer pair 2

    Microarray probesets 78
Other
Accession IDs
less
MGI:3646881
References
more
  • Summaries
    All 22
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:123065 Xu X, et al., Hemicentins assemble on diverse epithelia in the mouse. J Histochem Cytochem. 2007 Feb;55(2):119-26
  • Latest
    J:192188 Zhao Y, et al., Cross-reactivity of anti-programmed death ligand 2 polyclonal antibody in mouse tissues. Sci China Life Sci. 2012 Nov;55(11):940-7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory