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Ascl5 Gene Detail
Summary
  • Symbol
    Ascl5
  • Name
    achaete-scute family bHLH transcription factor 5
  • Synonyms
    Ascl5-ps, bHLHa47, LOC226439
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685043
    NCBI Gene: 226439
Location & Maps
more
  • Genetic Map
    Chromosome 1, 59.54 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    ASCL5, achaete-scute family bHLH transcription factor 5
  • Vertebrate Orthologs
    7
  • Human Ortholog
    ASCL5, achaete-scute family bHLH transcription factor 5
    Orthology source: HGNC, HomoloGene
  • Synonyms
    bHLHa47
  • Links
    NCBI Gene ID: 647219
    neXtProt AC: NX_Q7RTU5

  • Chr Location
    1q32.1; chr1:201113953-201115372 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    2
  • Radiation induced
    1
  • Genomic Mutations
    3 involving Ascl5
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000042967 VEGA Gene Model | MGI Sequence Detail 567 C57BL/6J ±  kb
transcript OTTMUST00000112803 VEGA | MGI Sequence Detail 567 Not Applicable  
polypeptide OTTMUSP00000063185 VEGA | MGI Sequence Detail 188 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    20 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR015660 Achaete-scute transcription factor-related
    IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Molecular
Reagents
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  • All nucleic 2
    cDNA 2
References
more
  • Summaries
    All 14
    Developmental Gene Expression 2
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:91257 Gray PA, et al., Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory