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Hipk4 Gene Detail
Summary
  • Symbol
    Hipk4
  • Name
    homeodomain interacting protein kinase 4
  • Synonyms
    LOC233020
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685008
    NCBI Gene: 233020
Location & Maps
more
  • Sequence Map
    Chr7:27523267-27531175 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7909 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 15.92 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    HIPK4, homeodomain interacting protein kinase 4
  • Vertebrate Orthologs
    6
  • Human Ortholog
    HIPK4, homeodomain interacting protein kinase 4
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 147746
    neXtProt AC: NX_Q8NE63

  • Chr Location
    19q13.2; chr19:40379271-40390221 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    7
  • Gene trapped
    3
  • Targeted
    4
  • Incidental Mutations
    APF , CvDC
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022752 VEGA Gene Model | MGI Sequence Detail 7909 C57BL/6J ±  kb
transcript OTTMUST00000054609 VEGA | MGI Sequence Detail 2409 Not Applicable  
polypeptide OTTMUSP00000026083 VEGA | MGI Sequence Detail 616 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    63 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000008569 homeodomain-interacting protein kinase 4
  • EC
  • InterPro Domains
    IPR017441 Protein kinase, ATP binding site
    IPR000719 Protein kinase domain
    IPR011009 Protein kinase-like domain
    IPR008271 Serine/threonine-protein kinase, active site
Molecular
Reagents
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  • All nucleic 6
    cDNA 6

    Microarray probesets 1
References
more
  • Summaries
    All 24
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory