About   Help   FAQ
Asap3 Gene Detail
Summary
  • Symbol
    Asap3
  • Name
    ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
  • Synonyms
    9430088F20Rik, Ddefl1, UPLC1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684986
    NCBI Gene: 230837
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:136206365-136245216 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 68.34 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    553 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684986
protein coding gene Chr4:136206350-136246577 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028962
protein coding gene Chr4:138737473-138777620 (+)
A/J MGP_AJ_G0028921
protein coding gene Chr4:132839694-132878385 (+)
AKR/J MGP_AKRJ_G0028873
protein coding gene Chr4:136679974-136723546 (+)
BALB/cJ MGP_BALBcJ_G0028945
protein coding gene Chr4:133501494-133540903 (+)
C3H/HeJ MGP_C3HHeJ_G0028659
protein coding gene Chr4:136956960-136996540 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029386
protein coding gene Chr4:143656493-143706169 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026657
protein coding gene Chr4:125875426-125913835 (+)
CAST/EiJ MGP_CASTEiJ_G0028091
protein coding gene Chr4:135097273-135137966 (+)
CBA/J MGP_CBAJ_G0028624
protein coding gene Chr4:147590052-147640405 (+)
DBA/2J MGP_DBA2J_G0028773
protein coding gene Chr4:133257007-133296005 (+)
FVB/NJ MGP_FVBNJ_G0028740
protein coding gene Chr4:132200685-132239538 (+)
LP/J MGP_LPJ_G0028872
protein coding gene Chr4:138827882-138871414 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028766
protein coding gene Chr4:151835335-151885153 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029424
protein coding gene Chr4:137137977-137177603 (+)
PWK/PhJ MGP_PWKPhJ_G0027811
protein coding gene Chr4:130030896-130071045 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027637
protein coding gene Chr4:132958402-132998683 (+)
WSB/EiJ MGP_WSBEiJ_G0028169
protein coding gene Chr4:137305441-137348679 (+)



Homology
more
  • Human Ortholog
    ASAP3, ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
  • Vertebrate Orthologs
    7
  • Human Ortholog
    ASAP3, ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ACAP4, CENTB6, DDEFL1, UPLC1
  • Links
    NCBI Gene ID: 55616
    neXtProt AC: NX_Q8TDY4
    UniProt: Q8TDY4

  • Chr Location
    1p36.12; chr1:23428563-23484631 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036995 Ensembl Gene Model | MGI Sequence Detail 38852 C57BL/6J ±  kb
transcript ENSMUST00000047526 Ensembl | MGI Sequence Detail 4225 Not Applicable  
polypeptide ENSMUSP00000041899 Ensembl | MGI Sequence Detail 904 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 31
    cDNA 31

    Microarray probesets 2
References
more
  • Summaries
    All 30
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
  • Latest
    J:262460 Qian J, et al., ASAP3 regulates microvilli structure in parietal cells and presents intervention target for gastric acidity. Signal Transduct Target Ther. 2017;2:17003

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/24/2020
MGI 6.15
The Jackson Laboratory