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Ndufb6 Gene Detail
Summary
  • Symbol
    Ndufb6
  • Name
    NADH:ubiquinone oxidoreductase subunit B6
  • Synonyms
    LOC230075
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684983
    NCBI Gene: 230075
  • Gene Overview
    MyGene.info: NDUFB6
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:40270591-40279421 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 20.24 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    50 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684983
protein coding gene Chr4:40270591-40279421 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028143
protein coding gene Chr4:38125481-38136545 (-)
A/J MGP_AJ_G0028101
protein coding gene Chr4:36713655-36722797 (-)
AKR/J MGP_AKRJ_G0028064
protein coding gene Chr4:37609195-37623978 (-)
BALB/cJ MGP_BALBcJ_G0028113
protein coding gene Chr4:37016697-37026568 (-)
C3H/HeJ MGP_C3HHeJ_G0027841
protein coding gene Chr4:38179261-38188319 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028554
protein coding gene Chr4:39567066-39577927 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025895
protein coding gene Chr4:34413074-34421572 (-)
CAST/EiJ MGP_CASTEiJ_G0027297
protein coding gene Chr4:37849257-37857702 (-)
CBA/J MGP_CBAJ_G0027813
protein coding gene Chr4:40898832-40907501 (-)
DBA/2J MGP_DBA2J_G0027957
protein coding gene Chr4:36624482-36633806 (-)
FVB/NJ MGP_FVBNJ_G0027924
protein coding gene Chr4:35973649-35983715 (-)
LP/J MGP_LPJ_G0028065
protein coding gene Chr4:38193209-38202007 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027957
protein coding gene Chr4:44266314-44275186 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028613
protein coding gene Chr4:37730886-37739429 (-)
PWK/PhJ MGP_PWKPhJ_G0027015
protein coding gene Chr4:36611624-36620280 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026843
protein coding gene Chr4:37468974-37477400 (-)
WSB/EiJ MGP_WSBEiJ_G0027373
protein coding gene Chr4:37727900-37738125 (-)



Homology
more
  • Human Ortholog
    NDUFB6, NADH:ubiquinone oxidoreductase subunit B6
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NDUFB6, NADH:ubiquinone oxidoreductase subunit B6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    B17, CI
  • Links
    NCBI Gene ID: 4712
    neXtProt AC: NX_O95139
    UniProt: O95139

  • Chr Location
    9p21.1; chr9:32553526-32573184 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 1864
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: NDUFB6
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    11
  • Chemically and radiation induced
    1
  • Gene trapped
    9
  • Targeted
    1
  • Genomic Mutations
    1 involving Ndufb6
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 230075 NCBI Gene Model | MGI Sequence Detail 8831 C57BL/6J ±  kb
transcript NM_001033305 RefSeq | MGI Sequence Detail 682 C57BL/6  
polypeptide Q3UIU2 UniProt | EBI | MGI Sequence Detail 128 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 29
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:172354 Wirtz S, et al., Region-Specific Expression of Mitochondrial Complex I Genes during Murine Brain Development. PLoS One. 2011;6(4):e18897

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory