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Ndufb6 Gene Detail
Summary
  • Symbol
    Ndufb6
  • Name
    NADH:ubiquinone oxidoreductase subunit B6
  • Synonyms
    LOC230075
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684983
    NCBI Gene: 230075
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:40270591-40279421 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 20.24 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    276 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684983
 protein coding gene Chr4:40270591-40279421 (-)
129S1/SvImJ ENSMUSG00200003774
 protein coding gene Chr4:37112427-37121257 (-)
A/J ENSMUSG00195003372
 protein coding gene Chr4:37492791-37501621 (-)
AKR/J ENSMUSG00220028593
 protein coding gene Chr4:37319151-37327981 (-)
BALB/cJ ENSMUSG00180019415
 protein coding gene Chr4:37072507-37081337 (-)
C3H/HeJ ENSMUSG00175021946
 protein coding gene Chr4:37458300-37467130 (-)
C57BL/6NJ ENSMUSG00215021570
 protein coding gene Chr4:37091096-37099926 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025895
 protein coding gene Chr4:34413074-34421572 (-)
CAST/EiJ ENSTCUG00005004660
 protein coding gene Chr4:36969065-36977512 (-)
CBA/J ENSMUSG00210007567
 protein coding gene Chr4:37154468-37163298 (-)
DBA/2J ENSMUSG00185006318
 protein coding gene Chr4:37228077-37236907 (-)
FVB/NJ ENSMUSG00205026655
 protein coding gene Chr4:36785152-36793982 (-)
JF1/MsJ ENSUMUG00000009127
 protein coding gene Chr4:37147906-37156551 (-)
LP/J ENSMUSG00230000846
 protein coding gene Chr4:40605835-40614665 (-)
NOD/ShiLtJ ENSMUSG00190005878
 protein coding gene Chr4:37182253-37191083 (-)
NZO/HlLtJ ENSMUSG00225006505
 protein coding gene Chr4:44485063-44493893 (-)
PWK/PhJ ENSLUMG00010006053
 protein coding gene Chr4:36672727-36681403 (-)
SPRET/EiJ ENSMSPG00010021845
 protein coding gene Chr4:37667391-37675817 (-)
WSB/EiJ ENSIUOG00005046598
 protein coding gene Chr4:37047232-37056063 (-)



Homology
more
  • Human Ortholog
    NDUFB6, NADH:ubiquinone oxidoreductase subunit B6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NDUFB6, NADH:ubiquinone oxidoreductase subunit B6
  • Synonyms
    B17, CI
  • Links
    NCBI Gene ID: 4712
    UniProt: O95139

  • Chr Location
    9p21.1; chr9:32553001-32573184 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    12
  • Chemically and radiation induced
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    8
  • Targeted
    1
  • Genomic Mutations
    1 involving Ndufb6
  • Find Mice (IMSR)
    11 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    693
  • Tissues
    95
  • cDNA Data
    8
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 230075 NCBI Gene Model | MGI Sequence Detail 8831 C57BL/6J ±  kb
transcript NM_001033305 RefSeq | MGI Sequence Detail 682 C57BL/6  
polypeptide Q3UIU2 UniProt | EBI | MGI Sequence Detail 128 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1
    Antibodies 1

    Microarray probesets 4
References
more
  • Summaries
    All 41
    Developmental Gene Expression 4
    Gene Ontology 12
    Phenotypes 5
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:370467 Gauberg J, et al., Spinal motor neuron development and metabolism are transcriptionally regulated by nuclear factor IA. Sci Adv. 2025 Aug;11(31):eadu3346
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory