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Mms22l Gene Detail
Summary
  • Symbol
    Mms22l
  • Name
    MMS22-like, DNA repair protein
  • Synonyms
    F730047E07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684980
    NCBI Gene: 212377
  • Gene Overview
    MyGene.info: MMS22L
Location & Maps
more
  • Sequence Map
    Chr4:24496451-24602950 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      106500 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 10.36 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    MMS22L, MMS22 like, DNA repair protein
  • Vertebrate Orthologs
    11
  • Human Ortholog
    MMS22L, MMS22 like, DNA repair protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C6orf167, dJ39B17.2
  • Links
    NCBI Gene ID: 253714
    neXtProt AC: NX_Q6ZRQ5

  • Chr Location
    6q16.1; chr6:97142161-97283437 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 18874
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;2 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MMS22L
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 2 genetic backgrounds
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation die prenatally. Heterozygous mice exhibit defects in pinna responses.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004797 VEGA Gene Model | MGI Sequence Detail 106500 C57BL/6J ±  kb
transcript OTTMUST00000010752 VEGA | MGI Sequence Detail 4478 Not Applicable  
polypeptide OTTMUSP00000005057 VEGA | MGI Sequence Detail 1238 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    650 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 52
    cDNA 52

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:213427 Adissu HA, et al., Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen. Dis Model Mech. 2014 May;7(5):515-24

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory