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Ciart Gene Detail
Summary
  • Symbol
    Ciart
  • Name
    circadian associated repressor of transcription
  • Synonyms
    Gm129, LOC229599
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684975
    NCBI Gene: 229599
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:95878500-95882242 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 41.42 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    13 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684975
protein coding gene Chr3:95878500-95882251 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027597
protein coding gene Chr3:96661549-96665306 (-)
A/J MGP_AJ_G0027556
protein coding gene Chr3:93632056-93635658 (-)
AKR/J MGP_AKRJ_G0027523
protein coding gene Chr3:95814959-95818713 (-)
BALB/cJ MGP_BALBcJ_G0027568
protein coding gene Chr3:93412713-93416458 (-)
C3H/HeJ MGP_C3HHeJ_G0027301
protein coding gene Chr3:96116068-96119822 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028016
protein coding gene Chr3:100206079-100209827 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025356
protein coding gene Chr3:89958841-89962445 (-)
CAST/EiJ MGP_CASTEiJ_G0026751
protein coding gene Chr3:95393322-95396918 (-)
CBA/J MGP_CBAJ_G0027278
protein coding gene Chr3:103873318-103877072 (-)
DBA/2J MGP_DBA2J_G0027417
protein coding gene Chr3:92923319-92927067 (-)
FVB/NJ MGP_FVBNJ_G0027388
protein coding gene Chr3:91001242-91005019 (-)
LP/J MGP_LPJ_G0027526
protein coding gene Chr3:97973696-97977804 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027415
protein coding gene Chr3:110001846-110005623 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028070
protein coding gene Chr3:95463030-95467172 (-)
PWK/PhJ MGP_PWKPhJ_G0026479
protein coding gene Chr3:92819404-92824397 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026300
protein coding gene Chr3:93753944-93757687 (-)
WSB/EiJ MGP_WSBEiJ_G0026833
protein coding gene Chr3:95854367-95858248 (-)



Homology
more
  • Human Ortholog
    CIART, circadian associated repressor of transcription
  • Vertebrate Orthologs
    6
  • Human Ortholog
    CIART, circadian associated repressor of transcription
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C1orf51, CHRONO, GM129
  • Links
    NCBI Gene ID: 148523
    neXtProt AC: NX_Q8N365
    UniProt: Q8N365

  • Chr Location
    1q21.2; chr1:150282533-150287093 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 3 alleles in 3 genetic backgrounds
    1 phenotype from multigenic genotypes
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Ciart
  • Incidental Mutations
  • Find Mice (IMSR)
Null mutants have slightly prolonged expression of circadian genes
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 229599 NCBI Gene Model | MGI Sequence Detail 3743 C57BL/6J ±  kb
transcript NM_001033302 RefSeq | MGI Sequence Detail 1395 C57BL/6  
polypeptide Q3TQ03 UniProt | EBI | MGI Sequence Detail 375 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR031373 Circadian-associated transcriptional repressor
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 3
References
more
  • Summaries
    All 31
    Diseases 1
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:33331 Nishiguchi S, et al., A catalogue of genes in mouse embryonal carcinoma F9 cells identified with expressed sequence tags. J Biochem. 1996 Apr;119(4):749-67
  • Latest
    J:209571 Goriki A, et al., A novel protein, CHRONO, functions as a core component of the mammalian circadian clock. PLoS Biol. 2014 Apr;12(4):e1001839

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/18/2019
MGI 6.14
The Jackson Laboratory