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Gm128 Gene Detail
Summary
  • Symbol
    Gm128
  • Name
    predicted gene 128
  • Synonyms
    LOC229588, Ment, Pmis1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684974
    NCBI Gene: 229588
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:95236920-95241109 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 40.74 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    24 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684974
protein coding gene Chr3:95236920-95241598 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027577
protein coding gene Chr3:95944458-95949135 (-)
A/J MGP_AJ_G0027536
protein coding gene Chr3:92978960-92983692 (-)
AKR/J MGP_AKRJ_G0027503
protein coding gene Chr3:95125071-95131629 (-)
BALB/cJ MGP_BALBcJ_G0027548
protein coding gene Chr3:92756947-92761591 (-)
C3H/HeJ MGP_C3HHeJ_G0027281
protein coding gene Chr3:95411304-95415944 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027996
protein coding gene Chr3:99510795-99515473 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025336
protein coding gene Chr3:89340819-89345918 (-)
CAST/EiJ MGP_CASTEiJ_G0026731
protein coding gene Chr3:94694668-94701530 (-)
CBA/J MGP_CBAJ_G0027258
protein coding gene Chr3:103116688-103124524 (-)
DBA/2J MGP_DBA2J_G0027397
protein coding gene Chr3:92271229-92275895 (-)
FVB/NJ MGP_FVBNJ_G0027368
protein coding gene Chr3:90346441-90350979 (-)
LP/J MGP_LPJ_G0027506
protein coding gene Chr3:97249982-97254707 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027395
protein coding gene Chr3:109235443-109240120 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028050
protein coding gene Chr3:94782262-94786985 (-)
PWK/PhJ MGP_PWKPhJ_G0026459
protein coding gene Chr3:92149764-92154353 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026280
protein coding gene Chr3:93075707-93080385 (-)
WSB/EiJ MGP_WSBEiJ_G0026813
protein coding gene Chr3:95166122-95171615 (-)



Homology
more
  • Human Ortholog
    C1orf56, chromosome 1 open reading frame 56
  • Vertebrate Orthologs
    7
  • Human Ortholog
    C1orf56, chromosome 1 open reading frame 56
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MENT
  • Links
    NCBI Gene ID: 54964
    neXtProt AC: NX_Q9BUN1
    UniProt: Q9BUN1

  • Chr Location
    1q21.3; chr1:151047783-151051420 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
A targeted mutation results in slightly decreased fertilization rates for males, although normal litter sizes are produced. Phenotypic analysis of mice homozygous for a gene trap allele indicates no notable phenotype in any parameter tested.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 229588 NCBI Gene Model | MGI Sequence Detail 4190 C57BL/6J ±  kb
transcript NM_001024841 RefSeq | MGI Sequence Detail 1470 C57BL/6  
polypeptide Q569E4 UniProt | EBI | MGI Sequence Detail 350 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR029292 Methylated in normal thymocytes protein
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 2
References
more
  • Summaries
    All 28
    Diseases 1
    Gene Ontology 2
    Phenotypes 11
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:185714 Yamaguchi R, et al., Mice expressing aberrant sperm-specific protein PMIS2 produce normal-looking but fertilization-incompetent spermatozoa. Mol Biol Cell. 2012 Jul;23(14):2671-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory