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Defb21 Gene Detail
Summary
  • Symbol
    Defb21
  • Name
    defensin beta 21
  • Synonyms
    4930525K10Rik, LOC228782
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684967
    NCBI Gene: 403172
Location & Maps
more
  • Sequence Map
    Chr2:152572744-152574944 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2201 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 75.31 cM
  • Mapping Data
    1 experiment
Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Defb21
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015840 VEGA Gene Model | MGI Sequence Detail 2201 C57BL/6J ±  kb
transcript OTTMUST00000037656 VEGA | MGI Sequence Detail 427 Not Applicable  
polypeptide OTTMUSP00000016883 VEGA | MGI Sequence Detail 100 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    44 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR025933 Beta-defensin
Molecular
Reagents
less
  • All nucleic 3
    cDNA 1
    Other 2

    Microarray probesets 2
References
more
  • Summaries
    All 19
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
  • Latest
    J:226028 Lewandowski JP, et al., Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev Biol. 2015 Oct 1;406(1):92-103

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory