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Bpifb6 Gene Detail
Summary
  • Symbol
    Bpifb6
  • Name
    BPI fold containing family B, member 6
  • Synonyms
    Bpil3, LOC228796
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684965
    NCBI Gene: 228796
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:153742308-153754715 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 75.99 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    237 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684965
 protein coding gene Chr2:153742308-153754715 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026701
 protein coding gene Chr2:158609586-158621989 (+)
A/J MGP_AJ_G0026667
 protein coding gene Chr2:152221190-152233603 (+)
AKR/J MGP_AKRJ_G0026638
 protein coding gene Chr2:156699972-156712379 (+)
BALB/cJ MGP_BALBcJ_G0026677
 protein coding gene Chr2:152558816-152571219 (+)
C3H/HeJ MGP_C3HHeJ_G0026419
 protein coding gene Chr2:157076636-157089039 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027126
 protein coding gene Chr2:163234936-163247343 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024496
 protein coding gene Chr2:145793044-145807160 (+)
CAST/EiJ MGP_CASTEiJ_G0025880
 protein coding gene Chr2:157344953-157357359 (+)
CBA/J MGP_CBAJ_G0026398
 protein coding gene Chr2:169233082-169245485 (+)
DBA/2J MGP_DBA2J_G0026533
 protein coding gene Chr2:151447459-151459866 (+)
FVB/NJ MGP_FVBNJ_G0026499
 protein coding gene Chr2:149895928-149908337 (+)
LP/J MGP_LPJ_G0026638
 protein coding gene Chr2:158728303-158740706 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026521
 protein coding gene Chr2:173214353-173226766 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027181
 protein coding gene Chr2:156591367-156603774 (+)
PWK/PhJ MGP_PWKPhJ_G0025614
 protein coding gene Chr2:150977426-150989847 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025417
 protein coding gene Chr2:155449100-155460739 (+)
WSB/EiJ MGP_WSBEiJ_G0025950
 protein coding gene Chr2:157499840-157512248 (+)



Homology
more
  • Human Ortholog
    BPIFB6, BPI fold containing family B member 6
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BPIFB6, BPI fold containing family B member 6
  • Synonyms
    BPIL3, LPLUNC6
  • Links
    NCBI Gene ID: 128859
    neXtProt AC: NX_Q8NFQ5
    UniProt: Q8NFQ5

  • Chr Location
    20q11.21; chr20:33031648-33044108 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 228796 NCBI Gene Model | MGI Sequence Detail 12408 C57BL/6J ±  kb
transcript NM_199303 RefSeq | MGI Sequence Detail 1667 C57BL/6  
polypeptide Q8BU51 UniProt | EBI | MGI Sequence Detail 449 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000004797 BPI fold-containing family B member 6
    (term hierarchy)
  • InterPro Domains
    IPR017943 Bactericidal permeability-increasing protein, alpha/beta domain superfamily
    IPR001124 Lipid-binding serum glycoprotein, C-terminal
    IPR017942 Lipid-binding serum glycoprotein, N-terminal
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 1
References
more
  • Summaries
    All 21
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:89705 Bingle CD, et al., Phylogenetic and evolutionary analysis of the PLUNC gene family. Protein Sci. 2004 Feb;13(2):422-30
  • Latest
    J:174122 Bingle CD, et al., Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily. Biochem Soc Trans. 2011 Aug 1;39(4):977-83
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory