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Man1b1
Gene Detail
Symbol

Name
ID
Man1b1
mannosidase, alpha, class 1B, member 1
MGI:2684954
Synonyms
E430019H13Rik, LOC227619, MANA-ER
Feature Type
protein coding gene
Genetic Map
Chromosome 2
17.17 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:25332338-25352212 bp, + strand
From VEGA annotation of GRCm38

  19875 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5230  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: mannosyl-oligosaccharide 1,2-alpha-mannosidase, 1A type
Gene Tree: Man1b1

Human
homologs
Human Homolog MAN1B1, mannosidase, alpha, class 1B, member 1
NCBI Gene ID 11253
neXtProt AC  NX_Q9UKM7
Human Synonyms  ERMAN1, MANA-ER, MRT15
Human Chr (Location)  9q34; chr9:137086862-137109187 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human MAN1B1
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(3) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Man1b1 interacts with 187 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(84)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(85) cDNA(84) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000011996 (Evidence)
Ensembl Gene ModelENSMUSG00000036646 (Evidence)
Entrez Gene227619 (Evidence)
UniGene270798
DFCITC1575229, TC1595495
DoTSDT.489471, DT.91298541
NIA Mouse Gene IndexU001486
EC3.2.1.113
Consensus CDS ProjectCCDS15765.1
International Mouse Knockout Project StatusMan1b1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000011996 VEGA Gene Model | MGI Sequence Detail 19875 C57BL/6J ±  kb
transcript OTTMUST00000028418 VEGA | MGI Sequence Detail 3755 Not Applicable 
polypeptide OTTMUSP00000012873 VEGA | MGI Sequence Detail 658 Not Applicable 

For the selected sequences
All sequences(63) RefSeq(4) UniProt(11)
Polymorphisms
SNPs within 2kb(119 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001382 Glycoside hydrolase, family 47
Protein Ontology PR:000010103 endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
References
(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(29)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory