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Dnah7b Gene Detail
Summary
  • Symbol
    Dnah7b
  • Name
    dynein, axonemal, heavy chain 7B
  • Synonyms
    Dnahc7b, LOC227058
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684953
    NCBI Gene: 227058
  • Gene Overview
    MyGene.info: DNAH7
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr1:46066315-46373546 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      307232 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 23.96 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    DNAH7, dynein axonemal heavy chain 7
  • Vertebrate Orthologs
    12
  • Human Ortholog
    DNAH7, dynein axonemal heavy chain 7
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 56171
    neXtProt AC: NX_Q8WXX0
    UniProt: Q8WXX0

  • Chr Location
    2q32.3; chr2:195737604-196075188 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000046662 VEGA Gene Model | MGI Sequence Detail 307232 C57BL/6J ±  kb
transcript OTTMUST00000121260 VEGA | MGI Sequence Detail 12314 Not Applicable  
polypeptide OTTMUSP00000066885 VEGA | MGI Sequence Detail 4068 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    955 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • InterPro Domains
    IPR003593 AAA+ ATPase domain
    IPR026983 Dynein heavy chain
    IPR024317 Dynein heavy chain, AAA module D4
    IPR035706 Dynein heavy chain, ATP-binding dynein motor region D5
    IPR024743 Dynein heavy chain, coiled coil stalk
    IPR004273 Dynein heavy chain domain
    IPR013602 Dynein heavy chain, domain-2
    IPR035699 Dynein heavy chain, hydrolytic ATP-binding dynein motor region D1
    IPR018247 EF-Hand 1, calcium-binding site
    IPR002048 EF-hand domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 3
References
more
  • Summaries
    All 24
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:208266 Dong F, et al., Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm. J Cell Biol. 2014 Jan 20;204(2):203-13

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory