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Cfap221 Gene Detail
Summary
  • Symbol
    Cfap221
  • Name
    cilia and flagella associated protein 221
  • Synonyms
    Gm101, Pcdp1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684947
    NCBI Gene: 226356
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:119923341-119997234 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 52.54 cM, cytoband E2.3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    265 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684947
protein coding gene Chr1:119923340-120006958 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016400
protein coding gene Chr1:122697715-122766644 (-)
A/J MGP_AJ_G0016383
protein coding gene Chr1:118300794-118371273 (-)
AKR/J MGP_AKRJ_G0016348
protein coding gene Chr1:121787220-121855876 (-)
BALB/cJ MGP_BALBcJ_G0016343
protein coding gene Chr1:118561013-118633967 (-)
C3H/HeJ MGP_C3HHeJ_G0016169
protein coding gene Chr1:121952372-122022868 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016804
protein coding gene Chr1:127372666-127449936 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014517
protein coding gene Chr1:111951032-112025557 (-)
CAST/EiJ MGP_CASTEiJ_G0015750
protein coding gene Chr1:120733975-120812858 (-)
CBA/J MGP_CBAJ_G0016142
protein coding gene Chr1:131780125-131861280 (-)
DBA/2J MGP_DBA2J_G0016248
protein coding gene Chr1:117323323-117393812 (-)
FVB/NJ MGP_FVBNJ_G0016247
protein coding gene Chr1:116073355-116144738 (-)
LP/J MGP_LPJ_G0016319
protein coding gene Chr1:124041814-124119503 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016272
protein coding gene Chr1:137533615-137602616 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016840
protein coding gene Chr1:121498892-121576373 (-)
PWK/PhJ MGP_PWKPhJ_G0015536
protein coding gene Chr1:116298507-116373041 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015324
protein coding gene Chr1:120390286-120467556 (-)
WSB/EiJ MGP_WSBEiJ_G0015812
protein coding gene Chr1:121381175-121454851 (-)



Homology
more
  • Human Ortholog
    CFAP221, cilia and flagella associated protein 221
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CFAP221, cilia and flagella associated protein 221
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FAP221, PCDP1
  • Links
    NCBI Gene ID: 200373
    neXtProt AC: NX_Q4G0U5
    UniProt: Q4G0U5

  • Chr Location
    2q14.2; chr2:119544392-119688610 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036962 Ensembl Gene Model | MGI Sequence Detail 73894 C57BL/6J ±  kb
transcript ENSMUST00000174370 Ensembl | MGI Sequence Detail 2871 Not Applicable  
polypeptide ENSMUSP00000134576 Ensembl | MGI Sequence Detail 836 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:206387 McKenzie CW, et al., Enhanced response to pulmonary Streptococcus pneumoniae infection is associated with primary ciliary dyskinesia in mice lacking Pcdp1 and Spef2. Cilia. 2013;2(1):18

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory