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Eddm3b Gene Detail
Summary
  • Symbol
    Eddm3b
  • Name
    epididymal protein 3B
  • Synonyms
    Fam12
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684921
    NCBI Gene: 219026
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:51114565-51117791 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 26.38 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    76 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684921
protein coding gene Chr14:51114426-51117807 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021273
protein coding gene Chr14:45082126-45085348 (+)
A/J MGP_AJ_G0021228
protein coding gene Chr14:43729624-43732846 (+)
AKR/J MGP_AKRJ_G0021204
protein coding gene Chr14:45377425-45380647 (+)
BALB/cJ MGP_BALBcJ_G0021231
protein coding gene Chr14:43856597-43859819 (+)
C3H/HeJ MGP_C3HHeJ_G0021013
protein coding gene Chr14:45198716-45201938 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021667
protein coding gene Chr14:46931053-46934279 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019218
protein coding gene Chr14:43061092-43064414 (+)
CAST/EiJ MGP_CASTEiJ_G0020536
protein coding gene Chr14:42270758-42273979 (+)
CBA/J MGP_CBAJ_G0020980
protein coding gene Chr14:48387400-48390622 (+)
DBA/2J MGP_DBA2J_G0021104
protein coding gene Chr14:43624111-43627326 (+)
FVB/NJ MGP_FVBNJ_G0021083
protein coding gene Chr14:43253466-43256681 (+)
LP/J MGP_LPJ_G0021171
protein coding gene Chr14:45373354-45376576 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021111
protein coding gene Chr14:47899273-47902488 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021696
protein coding gene Chr14:44862080-44865302 (+)
PWK/PhJ MGP_PWKPhJ_G0020286
protein coding gene Chr14:40541189-40544487 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020111
protein coding gene Chr14:41037069-41040302 (+)
WSB/EiJ MGP_WSBEiJ_G0020589
protein coding gene Chr14:45062715-45065930 (+)



Homology
more
  • Human Ortholog
    EDDM3A, epididymal protein 3A
  • Vertebrate Orthologs
    7
  • Human Ortholog
    EDDM3A, epididymal protein 3A
    Orthology source: HGNC
  • Synonyms
    EP3A, FAM12A, HE3A, HE3ALPHA, HE3-ALPHA, RAM1
  • Links
    NCBI Gene ID: 10876
    neXtProt AC: NX_Q14507
    UniProt: Q14507

  • Chr Location
    14q11.2; chr14:20735946-20748380 (+)  GRCh38.p7

  • Human Ortholog
    EDDM3B, epididymal protein 3B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    EP3B, FAM12B, HE3B, HE3-BETA, RAM2
  • Links
    NCBI Gene ID: 64184
    neXtProt AC: NX_P56851
    UniProt: P56851

  • Chr Location
    14q11.2; chr14:20768427-20770948 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 219026 NCBI Gene Model | MGI Sequence Detail 3227 C57BL/6J ±  kb
    transcript NM_203508 RefSeq | MGI Sequence Detail 1393 C57BL/6  
    polypeptide NP_987104 RefSeq | MGI Sequence Detail 149 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • InterPro Domains
      IPR042402 Epididymal secretory protein E3-alpha/beta
      IPR023412 Ribonuclease A-domain
      IPR036816 Ribonuclease A-like domain superfamily
    Molecular
    Reagents
    less
    • All nucleic 8
      cDNA 8

      Microarray probesets 1
    References
    more
    • Summaries
      All 22
      Developmental Gene Expression 2
      Phenotypes 6
    • Earliest
      J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
    • Latest
      J:241013 Grassmeyer J, et al., Elf5 is a principal cell lineage specific transcription factor in the kidney that contributes to Aqp2 and Avpr2 gene expression. Dev Biol. 2017 Apr 01;424(1):77-89

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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    last database update
    10/08/2019
    MGI 6.14
    The Jackson Laboratory