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Stox1
Gene Detail
Symbol

Name
ID
Stox1
storkhead box 1
MGI:2684909
Synonyms
4732470K04Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 10
32.45 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr10:62659043-62726128 bp, - strand
From VEGA annotation of GRCm38

  67086 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:17649  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: STOX1
Gene Tree: Stox1

Human
homologs
STOX1, storkhead box 1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 219736
neXtProt AC: NX_Q6ZVD7

Human Synonyms: C10orf24, PEE4

Human Chr (Location): 10q22.1; chr10:68827537-68895453 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human STOX1

Mutations,
alleles, and
phenotypes
All mutations/alleles(34) : Gene trapped(32) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Stox1 interacts with 79 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (29 annotations)
Process cellular response to nitrosative stress, inner ear development, ...
Component cell cortex, centrosome, ...
Function RNA polymerase II regulatory region sequence-specific DNA binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(6)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: ZFIN stox1    NEW 
Molecular
reagents
All nucleic(6) cDNA(6)
Microarray probesets(1)
Other database
links
VEGA Gene Model OTTMUSG00000032815 (Evidence)
Ensembl Gene Model ENSMUSG00000036923 (Evidence)
Entrez Gene 216021 (Evidence)
UniGene 39821
DFCI TC1608255
DoTS DT.40169068
NIA Mouse Gene Index U031855
Consensus CDS Project CCDS48580.1
International Mouse Phenotyping Consortium Status Stox1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000032815 VEGA Gene Model | MGI Sequence Detail 67086 C57BL/6J ±  kb
transcript OTTMUST00000081734 VEGA | MGI Sequence Detail 3510 Not Applicable 
polypeptide OTTMUSP00000043763 VEGA | MGI Sequence Detail 990 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(4) UniProt(4)
Polymorphisms
SNPs within 2kb(235 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR019391 Storkhead-box protein, winged-helix domain
Protein Ontology PR:000015769 storkhead-box protein 1
References
(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:220542 Nie X, et al., Transcription factor STOX1 regulates proliferation of inner ear epithelial cells via the AKT pathway. Cell Prolif. 2015 Apr;48(2):209-20
All references(23)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory