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Tmprss11a
Gene Detail
 Symbol
Name
ID
Tmprss11a
transmembrane protease, serine 11a
MGI:2684853
Synonyms LOC194597
Feature Type protein coding gene
Genetic Map
Chromosome 5
43.56 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:86410410-86468990 bp, - strand
From VEGA annotation of GRCm38

  58581 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:62723  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: transmembrane serine protease, TMPRSS11A type
Gene Tree: Tmprss11a

Human
homologs
Human Homolog TMPRSS11A, transmembrane protease, serine 11A
NCBI Gene ID 339967
neXtProt AC  NX_Q6ZMR5
Human Synonyms  ECRG1
Human Chr (Location)  4q13.2; chr4:67910301-67963514 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(1) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mice for a targeted mutation appear normal.
 
Interactions
Tmprss11a interacts with 233 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process cell cycle, proteolysis
Component extracellular region, integral component of membrane, ...
Function catalytic activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (35)    Tissues (35)    Images (1)
Theiler Stages: 28
Assay TypeResults
RT-PCR 35
cDNA source data(3)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(4) cDNA(3) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000035104 (Evidence)
Ensembl Gene ModelENSMUSG00000072845 (Evidence)
Entrez Gene194597 (Evidence)
DFCITC1583470
DoTSDT.40175820
NIA Mouse Gene IndexU026348
EC3.4.21.-
Consensus CDS ProjectCCDS51531.1
International Mouse Knockout Project StatusTmprss11a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035104 VEGA Gene Model | MGI Sequence Detail 58581 C57BL/6J ±  kb
transcript OTTMUST00000089304 VEGA | MGI Sequence Detail 2657 Not Applicable 
polypeptide OTTMUSP00000048793 VEGA | MGI Sequence Detail 389 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(4) UniProt(1)
Polymorphisms SNPs within 2kb(396 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR017329 Peptidase S1A, HAT/DESC1
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR000082 SEA domain
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000016448 transmembrane protease serine 11A
References (Earliest) J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
(Latest) J:175364 Sales KU, et al., Expression and Genetic Loss of Function Analysis of the HAT/DESC Cluster Proteases TMPRSS11A and HAT. PLoS One. 2011;6(8):e23261
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory