|Human Homolog||LZTS1, leucine zipper, putative tumor suppressor 1|
|NCBI Gene ID||11178|
|Human Synonyms||F37, FEZ1|
|Human Chr (Location)||8p22; chr8:20246165-20303981 (-) GRCh38.p2|
|Disease Associations||(1) Diseases Associated with Human LZTS1|
Targeted heterozygous or homozygous inactivation of this gene results in increased incidence of both spontaneous and carcinogen-induced tumors. Homozygous null MEFs show accelerated mitotic progression, resistance to taxol- and nocodazole-induced M phase arrest, and impaired chromosome segregation.
|Protein Ontology||PR:000031112||leucine zipper putative tumor suppressor 1|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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